Ryanodine receptors: physiological function and deregulation in Alzheimer disease

Por Del Prete, Dolores, Checler, Frédéric, Chami, Mounia
Publicado em 2014

APP Is Cleaved by Bace1 in Pre-Synaptic Vesicles and Establishes a Pre-Synaptic Interactome, via Its Intracellular Domain, with Molecular Complexes that Regulate Pre-Synaptic Vesic...

Por Del Prete, Dolores, Lombino, Franco, Liu, Xinran, D'Adamio, Luciano
Publicado em 2014

Interaction of ApoE3 and ApoE4 isoforms with an ITM2b/BRI2 mutation linked to the Alzheimer disease-like Danish dementia: Effects on learning and memory

Por Biundo, Fabrizio, Ishiwari, Keita, Del Prete, Dolores, D’Adamio, Luciano
Publicado no Neurobiol Learn Mem (2015)

Deletion of the γ-secretase subunits Aph1B/C impairs memory and worsens the deficits of knock-in mice modeling the Alzheimer-like familial Danish dementia

Por Biundo, Fabrizio, Ishiwari, Keita, Del Prete, Dolores, D'Adamio, Luciano
Publicado no Oncotarget (2016)

Amyloid Precursor Protein (APP) May Act as a Substrate and a Recognition Unit for CRL4(CRBN) and Stub1 E3 Ligases Facilitating Ubiquitination of Proteins Involved in Presynaptic Fu...

Por Del Prete, Dolores, Rice, Richard C., Rajadhyaksha, Anjali M., D'Adamio, Luciano
Publicado no J Biol Chem (2016)

APP and APLP2 interact with the synaptic release machinery and facilitate transmitter release at hippocampal synapses

Por Fanutza, Tomas, Del Prete, Dolores, Ford, Michael J, Castillo, Pablo E, D’Adamio, Luciano
Publicado no eLife (2015)

Nuclear factor-κB regulates βAPP and β- and γ-secretases differently at physiological and supraphysiological Aβ concentrations.

Por Chami, Linda, Buggia-Prévot, Virginie, Duplan, Eric, Del Prete, Dolores, Chami, Mounia, Peyron, Jean-François, Checler, Frédéric
Publicado no J Biol Chem (2015)

Leaky Ryanodine receptors increases Amyloid-beta load and induces memory impairments in Tg2576 mouse model of Alzheimer disease

Por Oulès, Bénédicte, Del Prete, Dolores, Greco, Barbara, Zhang, Xuexin, Lauritzen, Inger, Trebak, Mohamed, Benfenati, Fabio, Checler, Frédéric, Chami, Mounia
Publicado em 2013

Ryanodine Receptor Blockade Reduces Amyloid-β Load and Memory Impairments in Tg2576 Mouse Model of Alzheimer Disease

Por Oulès, Bénédicte, Del Prete, Dolores, Greco, Barbara, Zhang, Xuexin, Lauritzen, Inger, Sevalle, Jean, Moreno, Sebastien, Paterlini-Bréchot, Patrizia, Trebak, Mohamed, Checler, Frédéric, Benfenati, Fabio, Chami, Mounia
Publicado em 2012

Localization and Processing of the Amyloid-β Protein Precursor in Mitochondria-Associated Membranes

Por Del Prete, Dolores, Suski, Jan M., Oulès, Bénédicte, Debayle, Delphine, Gay, Anne Sophie, Lacas-Gervais, Sandra, Bussiere, Renaud, Bauer, Charlotte, Pinton, Paolo, Paterlini-Bréchot, Patrizia, Wieckowski, Mariusz R., Checler, Frédéric, Chami, Mounia
Publicado no J Alzheimers Dis (2016)