Dissemination of CTX-M-Type Extended-Spectrum β-Lactamase Genes to Unusual Hosts

per Mugnaioli, Claudia, Luzzaro, Francesco, De Luca, Filomena, Brigante, Gioconda, Amicosante, Gianfranco, Rossolini, Gian Maria
Publicat 2005

Genetic and Biochemical Characterization of TRU-1, the Endogenous Class C β-Lactamase from Aeromonas enteropelogenes

per De Luca, Filomena, Giraud-Morin, Chantal, Rossolini, Gian Maria, Docquier, Jean-Denis, Fosse, Thierry
Publicat 2010

Biochemical Characterization of the POM-1 Metallo-β-Lactamase from Pseudomonas otitidis

per Borgianni, Luisa, De Luca, Filomena, Thaller, Maria Cristina, Chong, Yunsop, Rossolini, Gian Maria, Docquier, Jean-Denis
Publicat a Antimicrob Agents Chemother (2015)

Biochemical Characterization of VIM-39, a VIM-1-Like Metallo-β-Lactamase Variant from a Multidrug-Resistant Klebsiella pneumoniae Isolate from Greece

per Papagiannitsis, Costas C., Pollini, Simona, De Luca, Filomena, Rossolini, Gian Maria, Docquier, Jean-Denis, Hrabák, Jaroslav
Publicat a Antimicrob Agents Chemother (2015)

BEL-2, an Extended-Spectrum β-Lactamase with Increased Activity toward Expanded-Spectrum Cephalosporins in Pseudomonas aeruginosa

per Poirel, Laurent, Docquier, Jean-Denis, De Luca, Filomena, Verlinde, Annemie, Ide, Louis, Rossolini, Gian Maria, Nordmann, Patrice
Publicat 2010

Evolution to carbapenem-hydrolyzing activity in noncarbapenemase class D β-lactamase OXA-10 by rational protein design

per De Luca, Filomena, Benvenuti, Manuela, Carboni, Filippo, Pozzi, Cecilia, Rossolini, Gian Maria, Mangani, Stefano, Docquier, Jean-Denis
Publicat 2011

Structural Insight into Potent Broad-Spectrum Inhibition with Reversible Recyclization Mechanism: Avibactam in Complex with CTX-M-15 and Pseudomonas aeruginosa AmpC β-Lactamases

per Lahiri, Sushmita D., Mangani, Stefano, Durand-Reville, Thomas, Benvenuti, Manuela, De Luca, Filomena, Sanyal, Gautam, Docquier, Jean-Denis
Publicat 2013

Crystal Structure of the Narrow-Spectrum OXA-46 Class D β-Lactamase: Relationship between Active-Site Lysine Carbamylation and Inhibition by Polycarboxylates

per Docquier, Jean-Denis, Benvenuti, Manuela, Calderone, Vito, Giuliani, Francesco, Kapetis, Dimos, De Luca, Filomena, Rossolini, Gian Maria, Mangani, Stefano
Publicat 2010

Crystal Structure of the Pseudomonas aeruginosa BEL-1 Extended-Spectrum β-Lactamase and Its Complexes with Moxalactam and Imipenem

per Pozzi, Cecilia, De Luca, Filomena, Benvenuti, Manuela, Poirel, Laurent, Nordmann, Patrice, Rossolini, Gian Maria, Mangani, Stefano, Docquier, Jean-Denis
Publicat a Antimicrob Agents Chemother (2016)

Molecular Evolution of Metallo-β-Lactamase-Producing Pseudomonas aeruginosa in a Nosocomial Setting of High-Level Endemicity

per Lagatolla, Cristina, Edalucci, Elisabetta, Dolzani, Lucilla, Riccio, Maria Letizia, De Luca, Filomena, Medessi, Erica, Rossolini, Gian Maria, Tonin, Enrico Angelo
Publicat 2006

CTX-M-Type Extended-Spectrum β-Lactamases in Italy: Molecular Epidemiology of an Emerging Countrywide Problem

per Mugnaioli, Claudia, Luzzaro, Francesco, De Luca, Filomena, Brigante, Gioconda, Perilli, Mariagrazia, Amicosante, Gianfranco, Stefani, Stefania, Toniolo, Antonio, Rossolini, Gian Maria
Publicat 2006

Screen of Unfocused Libraries Identified Compounds with Direct or Synergistic Antibacterial Activity

per Mugnaini, Claudia, Sannio, Filomena, Brizzi, Antonella, Del Prete, Rosita, Simone, Tiziana, Ferraro, Teresa, De Luca, Filomena, Corelli, Federico, Docquier, Jean-Denis
Publicat a ACS Med Chem Lett (2020)

Evaluation of HER2 and p53 expression in predicting response to docetaxel-based first-line chemotherapy in advanced breast cancer

per Martini Leonardo, De Luca Filomena, Valsuani Chiara, Tartarelli Gianna, Puccetti Cheti, Siclari Olimpia, Viacava Paolo, Donati Sara, Camerini Andrea, Cavazzana Andrea, Amoroso Domenico
Publicat 2011-04-01

IND-6, a Highly Divergent IND-Type Metallo-β-Lactamase from Chryseobacterium indologenes Strain 597 Isolated in Burkina Faso

per Zeba, Boukaré, De Luca, Filomena, Dubus, Alain, Delmarcelle, Michael, Simporé, Jacques, Nacoulma, Odile G., Rossolini, Gian Maria, Frère, Jean-Marie, Docquier, Jean-Denis
Publicat 2009

Evaluation of HER2 and p53 expression in predicting response to docetaxel-based first-line chemotherapy in advanced breast cancer

per Camerini, Andrea, Donati, Sara, Viacava, Paolo, Siclari, Olimpia, Puccetti, Cheti, Tartarelli, Gianna, Valsuani, Chiara, De Luca, Filomena, Martini, Leonardo, Cavazzana, Andrea, Amoroso, Domenico
Publicat 2011

First Countrywide Survey of Acquired Metallo-β-Lactamases in Gram-Negative Pathogens in Italy

per Rossolini, Gian Maria, Luzzaro, Francesco, Migliavacca, Roberta, Mugnaioli, Claudia, Pini, Beatrice, De Luca, Filomena, Perilli, Mariagrazia, Pollini, Simona, Spalla, Melissa, Amicosante, Gianfranco, Toniolo, Antonio, Pagani, Laura
Publicat 2008

Virtual screening identifies broad-spectrum β-lactamase inhibitors with activity on clinically relevant serine- and metallo-carbapenemases

per Spyrakis, Francesca, Santucci, Matteo, Maso, Lorenzo, Cross, Simon, Gianquinto, Eleonora, Sannio, Filomena, Verdirosa, Federica, De Luca, Filomena, Docquier, Jean-Denis, Cendron, Laura, Tondi, Donatella, Venturelli, Alberto, Cruciani, Gabriele, Costi, Maria Paola
Publicat a Sci Rep (2020)

Computational and biological profile of boronic acids for the detection of bacterial serine- and metallo-β-lactamases

per Santucci, Matteo, Spyrakis, Francesca, Cross, Simon, Quotadamo, Antonio, Farina, Davide, Tondi, Donatella, De Luca, Filomena, Docquier, Jean-Denis, Prieto, Ana Isabel, Ibacache, Claudia, Blázquez, Jesús, Venturelli, Alberto, Cruciani, Gabriele, Costi, Maria Paola
Publicat a Sci Rep (2017)

Discovery of a Novel Metallo-β-Lactamase Inhibitor That Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacteriaceae

per Everett, Martin, Sprynski, Nicolas, Coelho, Alicia, Castandet, Jérôme, Bayet, Maëlle, Bougnon, Juliette, Lozano, Clarisse, Davies, David T., Leiris, Simon, Zalacain, Magdalena, Morrissey, Ian, Magnet, Sophie, Holden, Kirsty, Warn, Peter, De Luca, Filomena, Docquier, Jean-Denis, Lemonnier, Marc
Publicat a Antimicrob Agents Chemother (2018)

4-(N-Alkyl- and -Acyl-amino)-1,2,4-triazole-3-thione Analogs as Metallo-β-Lactamase Inhibitors: Impact of 4-Linker on Potency and Spectrum of Inhibition

per Gavara, Laurent, Verdirosa, Federica, Legru, Alice, Mercuri, Paola Sandra, Nauton, Lionel, Sevaille, Laurent, Feller, Georges, Berthomieu, Dorothée, Sannio, Filomena, Marcoccia, Francesca, Tanfoni, Silvia, De Luca, Filomena, Gresh, Nohad, Galleni, Moreno, Docquier, Jean-Denis, Hernandez, Jean-François
Publicat a Biomolecules (2020)