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Evaluation of HER2 and p53 expression in predicting response to docetaxel-based first-line chemotherapy in advanced breast cancer

BACKGROUND: The human epidermal growth factor receptor 2 (HER2) and p53 pathways may be involved in chemotherapy sensitivity and/or resistance. We explore the value of HER2 and p53 status to foretell docetaxel sensitivity in advanced breast cancer. METHODS: HER2 and p53 expression was analysed in 36...

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Detalhes bibliográficos
Main Authors: Camerini, Andrea, Donati, Sara, Viacava, Paolo, Siclari, Olimpia, Puccetti, Cheti, Tartarelli, Gianna, Valsuani, Chiara, De Luca, Filomena, Martini, Leonardo, Cavazzana, Andrea, Amoroso, Domenico
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080331/
https://ncbi.nlm.nih.gov/pubmed/21481270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-30-38
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