Resveratrol chemosensitizes HER-2-overexpressing breast cancer cells to docetaxel chemoresistance by inhibiting docetaxel-mediated activation of HER-2–Akt axis

As breast cancer cells often develop chemoresistance, better therapeutic options are in search to circumvent it. Here we demonstrate that human epidermal growth factor receptor-2 (HER-2)-overexpressing breast cancer cells resist docetaxel-induced cytotoxicity by upregulating HER-2 and its activity d...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Vinod, B S, Nair, H H, Vijayakurup, V, Shabna, A, Shah, S, Krishna, A, Pillai, K S, Thankachan, S, Anto, R J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979566/
https://ncbi.nlm.nih.gov/pubmed/27551486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2015.61
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