Targeted therapy in chronic lymphocytic leukemia: past, present and future

Por Danilov, Alexey V
Publicado em 2013

Pericardial involvement by chronic lymphocytic leukemia/small lymphocytic lymphoma

Por Danilova, Olga V., Danilov, Alexey V.
Publicado no Blood (2015)

Gossypol Increases Expression of the Pro-apoptotic BH3-only Protein NOXA through a Novel Mechanism Involving Phospholipase A2, Cytoplasmic Calcium, and Endoplasmic Reticulum Stress

Por Soderquist, Ryan S., Danilov, Alexey V., Eastman, Alan
Publicado em 2014

The putative BH3 mimetic S1 sensitizes leukemia to ABT-737 by increasing reactive oxygen species, inducing endoplasmic reticulum stress, and upregulating the BH3-only protein NOXA

Por Soderquist, Ryan, Pletnev, Alexandre A., Danilov, Alexey V., Eastman, Alan
Publicado em 2014

Toward a cure for chronic lymphocytic leukemia: an attack on multiple fronts

Por Danilov, Alexey V, Soderquist, Ryan S, Bates, Darcy JP, Eastman, Alan
Publicado em 2013

Rapid induction of apoptosis in chronic lymphocytic leukemia cells by the microtubule disrupting agent BNC105

Por Bates, Darcy, Feris, Edmond J., Danilov, Alexey V., Eastman, Alan
Publicado no Cancer Biol Ther (2016)

Vinblastine rapidly induces NOXA and acutely sensitizes primary chronic lymphocytic leukemia cells to ABT-737

Por Bates, Darcy J. P., Danilov, Alexey V., Lowrey, Christopher H., Eastman, Alan
Publicado em 2013

Vincristine activates c-Jun N-terminal kinase in chronic lymphocytic leukaemia in vivo

Por Bates, Darcy J P, Lewis, Lionel D, Eastman, Alan, Danilov, Alexey V
Publicado no Br J Clin Pharmacol (2015)

Urticarial linear IgA bullous dermatosis (LABD) as a presenting sign of chronic lymphocytic leukemia (CLL)

Por Tiger, Jeffrey B., Rush, Jessica T., Barton, Dorothea T., Danilov, Alexey V., Chapman, M. Shane
Publicado no JAAD Case Rep (2015)

Dipeptidyl Peptidase 2 apoptosis assay determines the B-cell activation stage and predicts prognosis in chronic lymphocytic leukemia

Por Danilov, Alexey V., Danilova, Olga V., Brown, Jennifer R., Rabinowitz, Arthur, Klein, Andreas K., Huber, Brigitte T.
Publicado em 2010

Pro-apoptotic TP53 homolog TAp63 is repressed via epigenetic silencing and B-cell receptor signalling in chronic lymphocytic leukaemia

Por Humphries, Leigh A., Godbersen, J. Claire, Danilova, Olga V., Kaur, Prabhjot, Christensen, Brock C., Danilov, Alexey V.
Publicado em 2013

Pevonedistat, a Nedd8-activating enzyme inhibitor, sensitizes neoplastic B-cells to death receptor-mediated apoptosis

Por Paiva, Cody, Claire Godbersen, J., Rowland, Taylor, Danilova, Olga V., Danes, Christopher, Berger, Allison, Danilov, Alexey V.
Publicado no Oncotarget (2017)

DeltaNp63alpha-Mediated Induction of Epidermal Growth Factor Receptor Promotes Pancreatic Cancer Cell Growth and Chemoresistance

Por Danilov, Alexey V., Neupane, Divas, Nagaraja, Archana Sidalaghatta, Feofanova, Elena V., Humphries, Leigh Ann, DiRenzo, James, Korc, Murray
Publicado em 2011

FASN and CD36 predict survival in rituximab-treated diffuse large B-cell lymphoma

Por Danilova, Olga V., Dumont, Larry J., Levy, Norman B., Lansigan, Frederick, Kinlaw, William B., Danilov, Alexey V., Kaur, Prabhjot
Publicado no J Hematop (2013)

Correction: DeltaNp63alpha-Mediated Induction of Epidermal Growth Factor Receptor Promotes Pancreatic Cancer Cell Growth and Chemoresistance

Por Danilov, Alexey V., Neupane, Divas, Nagaraja, Archana Sidalaghatta, Feofanova, Elena V., Humphries, Leigh Ann, DiRenzo, James, Korc, Murray
Publicado no PLoS One (2018)

The Nedd8-activating enzyme inhibitor MLN4924 thwarts microenvironment-driven NFκB activation and induces apoptosis in chronic lymphocytic leukemia B-cells

Por Godbersen, J. Claire, Humphries, Leigh Ann, Danilova, Olga V., Kebbekus, Peter E., Brown, Jennifer R., Eastman, Alan, Danilov, Alexey V.
Publicado em 2014

Cyclin-Dependent Kinase Inhibitor P1446A Induces Apoptosis in a JNK/p38 MAPK-Dependent Manner in Chronic Lymphocytic Leukemia B-Cells

Por Paiva, Cody, Godbersen, J. Claire, Soderquist, Ryan S., Rowland, Taylor, Kilmarx, Sumner, Spurgeon, Stephen E., Brown, Jennifer R., Srinivasa, Sreesha P., Danilov, Alexey V.
Publicado no PLoS One (2015)

Feasibility of interim positron emission tomography (PET)-adapted therapy in HIV-positive patients with advanced Hodgkin Lymphoma (HL): a sub-analysis of SWOG S0816 phase 2 trial

Por Danilov, Alexey V., Li, Hongli, Press, Oliver W., Shapira, Ilan, Swinnen, Lode J., Noy, Ariela, Reid, Erin, Smith, Sonali M., Friedberg, Jonathan W.
Publicado no Leuk Lymphoma (2016)

Effect of ketoconazole, a strong CYP3A inhibitor, on the pharmacokinetics of venetoclax, a BCL‐2 inhibitor, in patients with non‐Hodgkin lymphoma

Por Agarwal, Suresh K., Salem, Ahmed Hamed, Danilov, Alexey V., Hu, Beibei, Puvvada, Soham, Gutierrez, Martin, Chien, David, Lewis, Lionel D., Wong, Shekman L.
Publicado no Br J Clin Pharmacol (2017)

A Phase I dose-ranging study of Bendamustine and Rituximab (BR) in chronic lymphocytic leukemia (CLL) patients with comorbidities

Por Danilov, Alexey V., Lewis, Lionel D., Lansigan, Frederick, Roudaia, Liya, Findley, Darcie L., Jones, Susan Y., Highhouse, Brian, Beaulieu, Bernard B., Brown, Jennifer R.
Publicado no Br J Haematol (2016)