Rapid induction of apoptosis in chronic lymphocytic leukemia cells by the microtubule disrupting agent BNC105

Microtubule targeting agents, such as vinblastine, are usually thought to arrest cells in mitosis and subsequently induce apoptosis. However, they can also cause rapid induction of apoptosis in a cell-cycle phase independent manner. BNC105 is a novel vascular and microtubule disrupting drug that als...

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Bibliografiska uppgifter
I publikationen:Cancer Biol Ther
Huvudupphovsmän: Bates, Darcy, Feris, Edmond J., Danilov, Alexey V., Eastman, Alan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2016
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847999/
https://ncbi.nlm.nih.gov/pubmed/26891146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1139245
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