Microtubule disrupting agent‐mediated inhibition of cancer cell growth is associated with blockade of autophagic flux and simultaneous induction of apoptosis

OBJECTIVES: Given that autophagy inhibition is a feasible way to enhance sensitivity of cancer cells towards chemotherapeutic agents, identifying potent autophagy inhibitor has obvious clinical relevance. Here, we investigated ability of TN‐16, a microtubule disrupting agent, on modulation of autoph...

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Bibliographic Details
Published in:Cell Prolif
Main Authors: Hasanain, Mohammad, Sahai, Rohit, Pandey, Praveen, Maheshwari, Mayank, Choyal, Kuldeep, Gandhi, Deepa, Singh, Akhilesh, Singh, Kavita, Mitra, Kalyan, Datta, Dipak, Sarkar, Jayanta
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162801/
https://ncbi.nlm.nih.gov/pubmed/32167212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.12749
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