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Regulation of autophagic flux by CHIP

Autophagy is a major degradation system which processes substrates through the steps of autophagosome formation, autophagosome-lysosome fusion, and substrate degradation. Aberrant autophagic flux is present in many pathological conditions including neurodegeneration and tumors. CHIP/STUB1, an E3 lig...

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Detalhes bibliográficos
Publicado no:Neurosci Bull
Main Authors: Guo, Dongkai, Ying, Zheng, Wang, Hongfeng, Chen, Dong, Gao, Feng, Ren, Haigang, Wang, Guanghui
Formato: Artigo
Idioma:Inglês
Publicado em: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5563714/
https://ncbi.nlm.nih.gov/pubmed/26219223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-015-1543-7
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