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Microtubule destabilising agents: far more than just antimitotic anticancer drugs

Vinca alkaloids have been approved as anticancer drugs for more than 50 years. They have been classified as cytotoxic chemotherapy drugs that act during cellular mitosis, enabling them to target fast growing cancer cells. With the evolution of cancer drug development there has been a shift towards n...

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Publicat a:Br J Clin Pharmacol
Autors principals: Bates, Darcy, Eastman, Alan
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237681/
https://ncbi.nlm.nih.gov/pubmed/27620987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13126
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