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Microtubule destabilising agents: far more than just antimitotic anticancer drugs

Vinca alkaloids have been approved as anticancer drugs for more than 50 years. They have been classified as cytotoxic chemotherapy drugs that act during cellular mitosis, enabling them to target fast growing cancer cells. With the evolution of cancer drug development there has been a shift towards n...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Bates, Darcy, Eastman, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5237681/
https://ncbi.nlm.nih.gov/pubmed/27620987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13126
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