The ubiquitin system: from cell signalling to disease biology and new therapeutic opportunities

由 Damgaard, Rune Busk
發表在 Cell Death Differ (2021)

Met1-linked ubiquitin signalling in health and disease: inflammation, immunity, cancer, and beyond

由 Jahan, Akhee Sabiha, Elbæk, Camilla Reiter, Damgaard, Rune Busk
發表在 Cell Death Differ (2021)

OTULIN deficiency in ORAS causes cell type‐specific LUBAC degradation, dysregulated TNF signalling and cell death

由 Damgaard, Rune Busk, Elliott, Paul R, Swatek, Kirby N, Maher, Eamonn R, Stepensky, Polina, Elpeleg, Orly, Komander, David, Berkun, Yackov
發表在 EMBO Mol Med (2019)

OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer

由 Damgaard, Rune Busk, Jolin, Helen E., Allison, Michael E. D., Davies, Susan E., Titheradge, Hannah L., McKenzie, Andrew N. J., Komander, David
發表在 Cell Death Differ (2020)

OTULIN restricts Met1-linked ubiquitination to control innate immune signaling

由 Fiil, Berthe Katrine, Damgaard, Rune Busk, Wagner, Sebastian Alexander, Keusekotten, Kirstin, Fritsch, Melanie, Bekker-Jensen, Simon, Mailand, Niels, Choudhary, Chunaram, Komander, David, Gyrd-Hansen, Mads
出版 2013

Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling

由 Damgaard, Rune Busk, Fiil, Berthe Katrine, Speckmann, Carsten, Yabal, Monica, zur Stadt, Udo, Bekker-Jensen, Simon, Jost, Philipp J, Ehl, Stephan, Mailand, Niels, Gyrd-Hansen, Mads
出版 2013

CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling

由 Hrdinka, Matous, Fiil, Berthe Katrine, Zucca, Mattia, Leske, Derek, Bagola, Katrin, Yabal, Monica, Elliott, Paul R., Damgaard, Rune Busk, Komander, David, Jost, Philipp J., Gyrd-Hansen, Mads
發表在 Cell Rep (2016)

OTULIN Antagonizes LUBAC Signaling by Specifically Hydrolyzing Met1-Linked Polyubiquitin

由 Keusekotten, Kirstin, Elliott, Paul Ronald, Glockner, Laura, Fiil, Berthe Katrine, Damgaard, Rune Busk, Kulathu, Yogesh, Wauer, Tobias, Hospenthal, Manuela Kathrin, Gyrd-Hansen, Mads, Krappmann, Daniel, Hofmann, Kay, Komander, David
出版 2013

The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity

由 Damgaard, Rune Busk, Walker, Jennifer A., Marco-Casanova, Paola, Morgan, Neil V., Titheradge, Hannah L., Elliott, Paul R., McHale, Duncan, Maher, Eamonn R., McKenzie, Andrew N.J., Komander, David
發表在 Cell (2016)