Aurora-A Kinase as a Promising Therapeutic Target in Cancer

Por D’Assoro, Antonino B., Haddad, Tufia, Galanis, Evanthia
Publicado no Front Oncol (2016)

Pleiotropic Effects of p300-mediated Acetylation on p68 and p72 RNA Helicase

Por Mooney, Steven M., Goel, Apollina, D'Assoro, Antonino B., Salisbury, Jeffrey L., Janknecht, Ralf
Publicado em 2010

Conversion to Sirolimus Therapy in Kidney Transplant Recipients with New Onset Diabetes Mellitus after Transplantation

Por Veroux, Massimiliano, Tallarita, Tiziano, Corona, Daniela, Sinagra, Nunziata, Giaquinta, Alessia, Zerbo, Domenico, Guerrieri, Carmela, D'Assoro, Antonino, Cimino, Sebastiano, Veroux, Pierfrancesco
Publicado em 2013

Inhibition of Cdk2 activity decreases Aurora-A kinase centrosomal localization and prevents centrosome amplification in breast cancer cells

Por LEONTOVICH, ALEXEY A., SALISBURY, JEFFREY L., VEROUX, MASSIMILIANO, TALLARITA, TIZIANO, BILLADEAU, DANIEL, McCUBREY, JAMES, INGLE, JAMES, GALANIS, EVANTHIA, D’ASSORO, ANTONINO B.
Publicado em 2013

Centrosome amplification drives chromosomal instability in breast tumor development

Por Lingle, Wilma L., Barrett, Susan L., Negron, Vivian C., D'Assoro, Antonino B., Boeneman, Kelly, Liu, Wanguo, Whitehead, Clark M., Reynolds, Carol, Salisbury, Jeffrey L.
Publicado em 2002

Raf-1 oncogenic signaling is linked to activation of mesenchymal to epithelial transition pathway in metastatic breast cancer cells

Por LEONTOVICH, ALEXEY A., ZHANG, SHUYA, QUATRARO, COSIMA, IANKOV, IANKO, VEROUX, PIER FRANCESCO, GAMBINO, MARIO W., DEGNIM, AMY, McCUBREY, JAMES, INGLE, JAMES, GALANIS, EVANTHIA, D'ASSORO, ANTONINO B.
Publicado em 2012

Progesterone receptor-B enhances estrogen responsiveness of breast cancer cells via scaffolding PELP1- and estrogen receptor-containing transcription complexes

Por Daniel, Andrea R., Gaviglio, Angela L., Knutson, Todd P., Ostrander, Julie H., D’Assoro, Antonino B., Ravindranathan, Preethi, Peng, Yan, Raj, Ganesh V., Yee, Douglas, Lange, Carol A.
Publicado em 2014

Inhibition of Cdk2 kinase activity selectively targets the CD44(+)/CD24(−/Low) stem-like subpopulation and restores chemosensitivity of SUM149PT triple-negative breast cancer cells...

Por OPYRCHAL, MATEUSZ, SALISBURY, JEFFREY L., IANKOV, IANKO, GOETZ, MATHEW P., McCUBREY, JAMES, GAMBINO, MARIO W., MALATINO, LORENZO, PUCCIA, GIUSEPPE, INGLE, JAMES N., GALANIS, EVANTHIA, D’ASSORO, ANTONINO B.
Publicado em 2014

Coordination of Centrosome Homeostasis and DNA Repair Is Intact in MCF-7 and Disrupted in MDA-MB 231 Breast Cancer Cells

Por Acu, Ilie D., Liu, Tieju, Suino-Powell, Kelly, Mooney, Steven M., D'Assoro, Antonino B., Rowland, Nicholas, Muotri, Alysson R., Correa, Ricardo G., Niu, Yun, Kumar, Rajiv, Salisbury, Jeffrey L.
Publicado em 2010

Abrogation of p53 function leads to metastatic transcriptome networks that typify tumor progression in human breast cancer xenografts

Por D'ASSORO, ANTONINO B., LEONTOVICH, ALEXEY, AMATO, ANGELA, AYERS-RINGLER, JENNIFER R., QUATRARO, COSIMA, HAFNER, KARI, JENKINS, ROBERT B., LIBRA, MASSIMO, INGLE, JAMES, STIVALA, FRANCA, GALANIS, EVANTHIA, SALISBURY, JEFFREY L.
Publicado no Int J Oncol (2010)

Aurora-A Mitotic Kinase Induces Endocrine Resistance through Down-Regulation of ERα Expression in Initially ERα+ Breast Cancer Cells

Por Opyrchal, Mateusz, Salisbury, Jeffrey L., Zhang, Shuya, McCubrey, James, Hawse, John, Goetz, Mattew P., Lomberk, Gwen A., Haddad, Tufia, Degnim, Amy, Lange, Carol, Ingle, James N., Galanis, Evanthia, D'Assoro, Antonino B.
Publicado em 2014

Molecular targeting of the Aurora-A/SMAD5 oncogenic axis restores chemosensitivity in human breast cancer cells

Por Opyrchal, Mateusz, Gil, Malgorzata, Salisbury, Jeffrey L., Goetz, Mathew P., Suman, Vera, Degnim, Amy, McCubrey, James, Haddad, Tufia, Iankov, Ianko, Kurokawa, Chenye B., Shumacher, Nicole, Ingle, James N., Galanis, Evanthia, D’Assoro, Antonino B.
Publicado no Oncotarget (2017)

GSK-3 as potential target for therapeutic intervention in cancer

Por McCubrey, James A., Steelman, Linda S., Bertrand, Fred E., Davis, Nicole M., Sokolosky, Melissa, Abrams, Steve L., Montalto, Giuseppe, D'Assoro, Antonino B., Libra, Massimo, Nicoletti, Ferdinando, Maestro, Roberta, Basecke, Jorg, Rakus, Dariusz, Gizak, Agnieszka, Demidenko, Zoya, Cocco, Lucio, Martelli, Alberto M., Cervello, Melchiorre
Publicado em 2014

Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention

Por Davis, Nicole M., Sokolosky, Melissa, Stadelman, Kristin, Abrams, Stephen L., Libra, Massimo, Candido, Saverio, Nicoletti, Ferdinando, Polesel, Jerry, Maestro, Roberta, D’Assoro, Antonino, Drobot, Lyudmyla, Rakus, Dariusz, Gizak, Agnieszka, Laidler, Piotr, Dulińska-Litewka, Joanna, Basecke, Joerg, Mijatovic, Sanja, Maksimovic-Ivanic, Danijela, Montalto, Giuseppe, Cervello, Melchiorre, Fitzgerald, Timothy L., Demidenko, Zoya N., Martelli, Alberto M., Cocco, Lucio, Steelman, Linda S., McCubrey, James A.
Publicado em 2014