Simulations of Membrane-Disrupting Peptides II: AMP Piscidin 1 Favors Surface Defects over Pores

per Perrin, B. Scott, Fu, Riqiang, Cotten, Myriam L., Pastor, Richard W.
Publicat a Biophys J (2016)

Lipopolysaccharide Simulations Are Sensitive to Phosphate Charge and Ion Parameterization

per Rice, Amy, Rooney, Mary T., Greenwood, Alexander I., Cotten, Myriam L., Wereszczynski, Jeff
Publicat a J Chem Theory Comput (2020)

Metal-ion Binding to Host Defense Peptide Piscidin 3 Observed in Phospholipid Bilayers by Magic Angle Spinning Solid-state NMR

per Rai, Ratan Kumar, Angelis, Anna De, Greenwood, Alexander, Opella, Stanley J., Cotten, Myriam L.
Publicat a Chemphyschem (2018)

How Oxygen Availability Affects the Antimicrobial Efficacy of Host Defense Peptides: Lessons Learned from Studying the Copper-Binding Peptides Piscidins 1 and 3

per Oludiran, Adenrele, Courson, David S., Stuart, Malia D., Radwan, Anwar R., Poutsma, John C., Cotten, Myriam L., Purcell, Erin B.
Publicat a Int J Mol Sci (2019)

Amphipathic Antimicrobial Piscidin in Magnetically Aligned Lipid Bilayers

per De Angelis, Anna A., Grant, Christopher V., Baxter, Matthew K., McGavin, Jason A., Opella, Stanley J., Cotten, Myriam L.
Publicat 2011

Copper regulates the interactions of antimicrobial piscidin peptides from fish mast cells with formyl peptide receptors and heparin

per Kim, So Young, Zhang, Fuming, Gong, Wanghua, Chen, Keqiang, Xia, Kai, Liu, Fei, Gross, Richard, Wang, Ji Ming, Linhardt, Robert J., Cotten, Myriam L.
Publicat a J Biol Chem (2018)

Copper-binding anticancer peptides from the piscidin family: an expanded mechanism that encompasses physical and chemical bilayer disruption

per Comert, Fatih, Heinrich, Frank, Chowdhury, Ananda, Schoeneck, Mason, Darling, Caitlin, Anderson, Kyle W., Libardo, M. Daben J., Angeles-Boza, Alfredo M., Silin, Vitalii, Cotten, Myriam L., Mihailescu, Mihaela
Publicat a Sci Rep (2021)

The host-defense peptide piscidin P1 reorganizes lipid domains in membranes and decreases activation energies in mechanosensitive ion channels

per Comert, Fatih, Greenwood, Alexander, Maramba, Joseph, Acevedo, Roderico, Lucas, Laura, Kulasinghe, Thulasi, Cairns, Leah S., Wen, Yi, Fu, Riqiang, Hammer, Janet, Blazyk, Jack, Sukharev, Sergei, Cotten, Myriam L., Mihailescu, Mihaela
Publicat a J Biol Chem (2019)

Nuclease activity gives an edge to host-defense peptide piscidin 3 over piscidin 1, rendering it more effective against persisters and biofilms

per Libardo, M. Daben J., Bahar, Ali A., Ma, Buyong, Fu, Riqiang, McCormick, Laura E., Zhao, Jun, McCallum, Scott A., Nussinov, Ruth, Ren, Dacheng, Angeles-Boza, Alfredo M., Cotten, Myriam L.
Publicat a FEBS J (2017)

A Potent Host Defense Peptide Triggers DNA Damage and Is Active against Multidrug-Resistant Gram-Negative Pathogens

per Juliano, Samuel A., Serafim, Leonardo F., Duay, Searle S., Chavez, Maria Heredia, Sharma, Gaurav, Rooney, Mary, Comert, Fatih, Pierce, Scott, Radulescu, Andrei, Cotten, Myriam L., Mihailescu, Mihaela, May, Eric R., Greenwood, Alexander I., Prabhakar, Rajeev, Angeles-Boza, Alfredo M.
Publicat a ACS Infect Dis (2020)

High-Resolution Structures and Orientations of Antimicrobial Peptides Piscidin 1 and Piscidin 3 in Fluid Bilayers Reveal Tilting, Kinking, and Bilayer Immersion

per Perrin, B. Scott, Tian, Ye, Fu, Riqiang, Grant, Christopher V., Chekmenev, Eduard Y., Wieczorek, William E., Dao, Alexander E., Hayden, Robert M., Burzynski, Caitlin M., Venable, Richard M., Sharma, Mukesh, Opella, Stanley J., Pastor, Richard W., Cotten, Myriam L.
Publicat 2014

Structure and Function in Antimicrobial Piscidins: Histidine Position, Directionality of Membrane Insertion, and pH-dependent Permeabilization

per Mihailescu, Mihaela, Sorci, Mirco, Seckute, Jolita, Silin, Vitalii I., Hammer, Janet, Perrin, B. Scott, Hernandez, Jorge I., Smajic, Nedzada, Shrestha, Akritee, Bogardus, Kimberly A., Greenwood, Alexander I., Fu, Riqiang, Blazyk, Jack, Pastor, Richard W., Nicholson, Linda K., Belfort, Georges, Cotten, Myriam L.
Publicat a J Am Chem Soc (2019)