Emergence and Targeting of Acquired and Hereditary Resistance to Multikinase RET Inhibition in Patients With RET-Altered Cancer

Autor Wirth, Lori J., Kohno, Takashi, Udagawa, Hibiki, Matsumoto, Shingo, Ishii, Genichiro, Ebata, Kevin, Tuch, Brian B., Zhu, Edward Y., Nguyen, Michele, Smith, Steve, Hanson, Lauren M., Burkard, Michael R., Cable, LouAnn, Blake, James F., Condroski, Kevin R., Brandhuber, Barbara J., Andrews, Steve, Rothenberg, S. Michael, Goto, Koichi
Vydáno v JCO Precis Oncol (2019)

Preclinical Characteristics of the Hepatitis C Virus NS3/4A Protease Inhibitor ITMN-191 (R7227)

Autor Seiwert, Scott D., Andrews, Steven W., Jiang, Yutong, Serebryany, Vladimir, Tan, Hua, Kossen, Karl, Rajagopalan, P. T. Ravi, Misialek, Shawn, Stevens, Sarah K., Stoycheva, Antitsa, Hong, Jin, Lim, Sharlene R., Qin, Xiaoli, Rieger, Robert, Condroski, Kevin R., Zhang, Hailong, Do, Mary Geck, Lemieux, Christine, Hingorani, Gary P., Hartley, Dylan P., Josey, John A., Pan, Lin, Beigelman, Leonid, Blatt, Lawrence M.
Vydáno 2008

Novel Series of Potent Glucokinase Activators Leading to the Discovery of AM-2394

Autor Dransfield, Paul J., Pattaropong, Vatee, Lai, Sujen, Fu, Zice, Kohn, Todd J., Du, Xiaohui, Cheng, Alan, Xiong, Yumei, Komorowski, Renee, Jin, Lixia, Conn, Marion, Tien, Eric, DeWolf, Walter E., Hinklin, Ronald J., Aicher, Thomas D., Kraser, Christopher F., Boyd, Steven A., Voegtli, Walter C., Condroski, Kevin R., Veniant-Ellison, Murielle, Medina, Julio C., Houze, Jonathan, Coward, Peter
Vydáno v ACS Med Chem Lett (2016)

C5-Alkyl-2-methylurea-Substituted Pyridines as a New Class of Glucokinase Activators

Autor Du, Xiaohui, Hinklin, Ronald J., Xiong, Yumei, Dransfield, Paul, Park, Jaehyeon, Kohn, Todd J., Pattaropong, Vatee, Lai, SuJen, Fu, Zice, Jiao, Xianyun, Chow, David, Jin, Lixia, Davda, Jasmine, Veniant, Murielle M., Anderson, Deborah A., Baer, Brian R., Bencsik, Josef R., Boyd, Steven A., Chicarelli, Mark Joseph, Mohr, Peter J., Wang, Bin, Condroski, Kevin R., DeWolf, Walter E., Conn, Marion, Tran, Thanhvien, Yang, Jerry, Aicher, Thomas D., Medina, Julio C., Coward, Peter, Houze, Jonathan B.
Vydáno v ACS Med Chem Lett (2014)

RET Solvent Front Mutations Mediate Acquired Resistance to Selective RET Inhibition in RET-Driven Malignancies

Autor Solomon, Benjamin J., Tan, Lavinia, Lin, Jessica J., Wong, Stephen Q., Hollizeck, Sebastian, Ebata, Kevin, Tuch, Brian B., Yoda, Satoshi, Gainor, Justin F., Sequist, Lecia V., Oxnard, Geoffrey R., Gautschi, Oliver, Drilon, Alexander, Subbiah, Vivek, Khoo, Christine, Zhu, Edward Y., Nguyen, Michele, Henry, Dahlia, Condroski, Kevin R., Kolakowski, Gabrielle R., Gomez, Eliana, Ballard, Joshua, Metcalf, Andrew T., Blake, James F., Dawson, Sarah-Jane, Blosser, Wayne, Stancato, Louis F., Brandhuber, Barbara J., Andrews, Steve, Robinson, Bruce G., Rothenberg, S. Michael
Vydáno v J Thorac Oncol (2020)