An Insulin-Sensitizing Thiazolidinedione, Which Minimally Activates PPARγ, Does Not Cause Bone Loss

由 Fukunaga, Tomohiro, Zou, Wei, Rohatgi, Nidhi, Colca, Jerry R., Teitelbaum, Steven L.
發表在 J Bone Miner Res (2015)

Treating fatty liver disease by modulating mitochondrial pyruvate metabolism

由 Colca, Jerry R., McDonald, William G., McCommis, Kyle S., Finck, Brian N.
發表在 Hepatol Commun (2017)

Novel insulin sensitizer MSDC-0602K improves insulinemia and fatty liver disease in mice, alone and in combination with liraglutide

由 Kamm, Dakota R., Pyles, Kelly D., Sharpe, Martin C., Healy, Laura N., Colca, Jerry R., McCommis, Kyle S.
發表在 J Biol Chem (2021)

Novel Insulin Sensitizer Modulates Nutrient Sensing Pathways and Maintains β-Cell Phenotype in Human Islets

由 Rohatgi, Nidhi, Aly, Haytham, Marshall, Connie A., McDonald, William G., Kletzien, Rolf F., Colca, Jerry R., McDaniel, Michael L.
出版 2013

An Evaluation of MSDC-0160, A Prototype mTOT Modulating Insulin Sensitizer, in Patients with Mild Alzheimer’s Disease

由 Shah, Raj C, Matthews, Dawn C, Andrews, Randolph D, Capuano, Ana W, Fleischman, Debra A, VanderLugt, James T, Colca, Jerry R
出版 2014

Loss of Mitochondrial Pyruvate Carrier 2 in Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling

由 McCommis, Kyle S., Chen, Zhouji, Fu, Xiaorong, McDonald, William G., Colca, Jerry R., Kletzien, Rolf F., Burgess, Shawn C., Finck, Brian N.
發表在 Cell Metab (2015)

Insulin Resistance and Metabolic Derangements in Obese Mice Are Ameliorated by a Novel Peroxisome Proliferator-activated Receptor γ-sparing Thiazolidinedione

由 Chen, Zhouji, Vigueira, Patrick A., Chambers, Kari T., Hall, Angela M., Mitra, Mayurranjan S., Qi, Nathan, McDonald, William G., Colca, Jerry R., Kletzien, Rolf F., Finck, Brian N.
出版 2012

Targeting the Mitochondrial Pyruvate Carrier Attenuates Fibrosis in a Mouse Model of Nonalcoholic Steatohepatitis

由 McCommis, Kyle S., Hodges, Wesley T., Brunt, Elizabeth M., Nalbantoglu, ILKe, McDonald, William G., Holley, Christopher, Fujiwara, Hideji, Schaffer, Jean E., Colca, Jerry R., Finck, Brian N.
發表在 Hepatology (2017)

The Beneficial Metabolic Effects of Insulin Sensitizers are not Attenuated by Mitochondrial Pyruvate Carrier 2 Hypomorphism

由 Vigueira, Patrick A., McCommis, Kyle S., Hodges, Wesley T., Schweitzer, George G., Cole, Serena L., Oonthonpan, Lalita, Taylor, Eric B., McDonald, William G., Kletzien, Rolf F., Colca, Jerry R., Finck, Brian N.
發表在 Exp Physiol (2017)

Mitochondrial Pyruvate Carrier 2 Hypomorphism in Mice Leads to Defects in Glucose-Stimulated Insulin Secretion

由 Vigueira, Patrick A., McCommis, Kyle S., Schweitzer, George G., Remedi, Maria S., Chambers, Kari T., Fu, Xiaorong, McDonald, William G., Cole, Serena L., Colca, Jerry R., Kletzien, Rolf F., Burgess, Shawn C., Finck, Brian N.
出版 2014

Insulin Sensitizing Pharmacology of Thiazolidinediones Correlates with Mitochondrial Gene Expression rather than Activation of PPARγ

由 Bolten, Charles W., Blanner, Patrick M., McDonald, William G., Staten, Nicholas R., Mazzarella, Richard A., Arhancet, Graciela B., Meier, Martin F., Weiss, David J., Sullivan, Patrick M., Hromockyj, Alexander E., Kletzien, Rolf F., Colca, Jerry R.
出版 2007

Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier

由 Divakaruni, Ajit S., Wiley, Sandra E., Rogers, George W., Andreyev, Alexander Y., Petrosyan, Susanna, Loviscach, Mattias, Wall, Estelle A., Yadava, Nagendra, Heuck, Alejandro P., Ferrick, David A., Henry, Robert R., McDonald, William G., Colca, Jerry R., Simon, Melvin I., Ciaraldi, Theodore P., Murphy, Anne N.
出版 2013

Identification of a Mitochondrial Target of Thiazolidinedione Insulin Sensitizers (mTOT)—Relationship to Newly Identified Mitochondrial Pyruvate Carrier Proteins

由 Colca, Jerry R., McDonald, William G., Cavey, Gregory S., Cole, Serena L., Holewa, Danielle D., Brightwell-Conrad, Angela S., Wolfe, Cindy L., Wheeler, Jean S., Coulter, Kristin R., Kilkuskie, Peter M., Gracheva, Elena, Korshunova, Yulia, Trusgnich, Michelle, Karr, Robert, Wiley, Sandra E., Divakaruni, Ajit S., Murphy, Anne N., Vigueira, Patrick A., Finck, Brian N., Kletzien, Rolf F.
出版 2013