iPSCs in Cardiovascular Drug Discovery

by Mercola, Mark, Colas, Alexandre, Willems, Erik
Published 2013

Early molecular events during retinoic acid induced differentiation of neuromesodermal progenitors

by Cunningham, Thomas J., Colas, Alexandre, Duester, Gregg
Published in Biol Open (2016)

Generation of First Heart Field-like Cardiac Progenitors and Ventricular-like Cardiomyocytes from Human Pluripotent Stem Cells

by Yu, Michael S., Spiering, Sean, Colas, Alexandre R.
Published in J Vis Exp (2018)

AlleleProfileR: A versatile tool to identify and profile sequence variants in edited genomes

by Bruyneel, Arne A. N., Colas, Alexandre R., Karakikes, Ioannis, Mercola, Mark
Published in PLoS One (2019)

Serum-Free Generation of Multipotent Mesoderm (Kdr-positive) Progenitor Cells in Mouse Embryonic Stem Cells For Functional Genomics Screening

by McKeithan, Wesley, Colas, Alexandre, Bushway, Paul J., Ray, Saugata, Mercola, Mark
Published 2012

Retinoic Acid Activity in Undifferentiated Neural Progenitors Is Sufficient to Fulfill Its Role in Restricting Fgf8 Expression for Somitogenesis

by Cunningham, Thomas J., Brade, Thomas, Sandell, Lisa L., Lewandoski, Mark, Trainor, Paul A., Colas, Alexandre, Mercola, Mark, Duester, Gregg
Published in PLoS One (2015)

Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis

by Colas, Alexandre R., McKeithan, Wesley L., Cunningham, Thomas J., Bushway, Paul J., Garmire, Lana X., Duester, Gregg, Subramaniam, Shankar, Mercola, Mark
Published 2012

Dietary Emulsifier Sodium Stearoyl Lactylate Alters Gut Microbiota in vitro and Inhibits Bacterial Butyrate Producers

by Elmén, Lisa, Zlamal, Jaime E., Scott, David A., Lee, Ryan B., Chen, Daniel J., Colas, Alexandre R., Rodionov, Dmitry A., Peterson, Scott N.
Published in Front Microbiol (2020)

An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes

by McKeithan, Wesley L., Savchenko, Alex, Yu, Michael S., Cerignoli, Fabio, Bruyneel, Arne A. N., Price, Jeffery H., Colas, Alexandre R., Miller, Evan W., Cashman, John R., Mercola, Mark
Published in Front Physiol (2017)

Silencing of CCR4-NOT complex subunits affects heart structure and function

by Elmén, Lisa, Volpato, Claudia B., Kervadec, Anaïs, Pineda, Santiago, Kalvakuri, Sreehari, Alayari, Nakissa N., Foco, Luisa, Pramstaller, Peter P., Ocorr, Karen, Rossini, Alessandra, Cammarato, Anthony, Colas, Alexandre R., Hicks, Andrew A., Bodmer, Rolf
Published in Dis Model Mech (2020)

PGC1/PPAR drive cardiomyocyte maturation at single cell level via YAP1 and SF3B2

by Murphy, Sean A., Miyamoto, Matthew, Kervadec, Anaïs, Kannan, Suraj, Tampakakis, Emmanouil, Kambhampati, Sandeep, Lin, Brian Leei, Paek, Sam, Andersen, Peter, Lee, Dong-Ik, Zhu, Renjun, An, Steven S., Kass, David A., Uosaki, Hideki, Colas, Alexandre R., Kwon, Chulan
Published in Nat Commun (2021)

Model system identification of novel congenital heart disease gene candidates: focus on RPL13

by Schroeder, Analyne M, Allahyari, Massoud, Vogler, Georg, Missinato, Maria A, Nielsen, Tanja, Yu, Michael S, Theis, Jeanne L, Larsen, Lars A, Goyal, Preeya, Rosenfeld, Jill A, Nelson, Timothy J, Olson, Timothy M, Colas, Alexandre R, Grossfeld, Paul, Bodmer, Rolf
Published in Hum Mol Genet (2019)

Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation

by Salomonis, Nathan, Schlieve, Christopher R., Pereira, Laura, Wahlquist, Christine, Colas, Alexandre, Zambon, Alexander C., Vranizan, Karen, Spindler, Matthew J., Pico, Alexander R., Cline, Melissa S., Clark, Tyson A., Williams, Alan, Blume, John E., Samal, Eva, Mercola, Mark, Merrill, Bradley J., Conklin, Bruce R.
Published 2010

Id genes are essential for early heart formation

by Cunningham, Thomas J., Yu, Michael S., McKeithan, Wesley L., Spiering, Sean, Carrette, Florent, Huang, Chun-Teng, Bushway, Paul J., Tierney, Matthew, Albini, Sonia, Giacca, Mauro, Mano, Miguel, Puri, Pier Lorenzo, Sacco, Alessandra, Ruiz-Lozano, Pilar, Riou, Jean-Francois, Umbhauer, Muriel, Duester, Gregg, Mercola, Mark, Colas, Alexandre R.
Published in Genes Dev (2017)

Acellular therapeutic approach for heart failure: in vitro production of extracellular vesicles from human cardiovascular progenitors

by El Harane, Nadia, Kervadec, Anaïs, Bellamy, Valérie, Pidial, Laetitia, Neametalla, Hany J, Perier, Marie-Cécile, Lima Correa, Bruna, Thiébault, Léa, Cagnard, Nicolas, Duché, Angéline, Brunaud, Camille, Lemitre, Mathilde, Gauthier, Jeanne, Bourdillon, Alexandra T, Renault, Marc P, Hovhannisyan, Yeranuhi, Paiva, Solenne, Colas, Alexandre R, Agbulut, Onnik, Hagège, Albert, Silvestre, Jean-Sébastien, Menasché, Philippe, Renault, Nisa K E
Published in Eur Heart J (2018)

Small Molecule Probe Reveals a Kinase Cascade that Links Stress Signaling to TCF/LEF and Wnt Responsiveness

by Cheng, Jiongjia, Tsuda, Masanao, Okolotowicz, Karl, Dwyer, Mary, Bushway, Paul J., Colas, Alexandre R., Lancman, Joseph J., Schade, Dennis, Perea-Gil, Isaac, Bruyneel, Arne A.N., Lee, Jaechol, Vadgama, Nirmal, Quach, Justine, McKeithan, Wesley L., Biechele, Travis L., Wu, Joseph C., Moon, Randall T., Si Dong, P. Duc, Karakikes, Ioannis, Cashman, John R., Mercola, Mark
Published in Cell Chem Biol (2021)

Patient-specific genomics and cross-species functional analysis implicate LRP2 in hypoplastic left heart syndrome

by Theis, Jeanne L, Vogler, Georg, Missinato, Maria A, Li, Xing, Nielsen, Tanja, Zeng, Xin-Xin I, Martinez-Fernandez, Almudena, Walls, Stanley M, Kervadec, Anaïs, Kezos, James N, Birker, Katja, Evans, Jared M, O'Byrne, Megan M, Fogarty, Zachary C, Terzic, André, Grossfeld, Paul, Ocorr, Karen, Nelson, Timothy J, Olson, Timothy M, Colas, Alexandre R, Bodmer, Rolf
Published in eLife (2020)