iPSCs in Cardiovascular Drug Discovery

per Mercola, Mark, Colas, Alexandre, Willems, Erik
Publicat 2013

Early molecular events during retinoic acid induced differentiation of neuromesodermal progenitors

per Cunningham, Thomas J., Colas, Alexandre, Duester, Gregg
Publicat a Biol Open (2016)

Generation of First Heart Field-like Cardiac Progenitors and Ventricular-like Cardiomyocytes from Human Pluripotent Stem Cells

per Yu, Michael S., Spiering, Sean, Colas, Alexandre R.
Publicat a J Vis Exp (2018)

AlleleProfileR: A versatile tool to identify and profile sequence variants in edited genomes

per Bruyneel, Arne A. N., Colas, Alexandre R., Karakikes, Ioannis, Mercola, Mark
Publicat a PLoS One (2019)

Serum-Free Generation of Multipotent Mesoderm (Kdr-positive) Progenitor Cells in Mouse Embryonic Stem Cells For Functional Genomics Screening

per McKeithan, Wesley, Colas, Alexandre, Bushway, Paul J., Ray, Saugata, Mercola, Mark
Publicat 2012

Retinoic Acid Activity in Undifferentiated Neural Progenitors Is Sufficient to Fulfill Its Role in Restricting Fgf8 Expression for Somitogenesis

per Cunningham, Thomas J., Brade, Thomas, Sandell, Lisa L., Lewandoski, Mark, Trainor, Paul A., Colas, Alexandre, Mercola, Mark, Duester, Gregg
Publicat a PLoS One (2015)

Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis

per Colas, Alexandre R., McKeithan, Wesley L., Cunningham, Thomas J., Bushway, Paul J., Garmire, Lana X., Duester, Gregg, Subramaniam, Shankar, Mercola, Mark
Publicat 2012

Dietary Emulsifier Sodium Stearoyl Lactylate Alters Gut Microbiota in vitro and Inhibits Bacterial Butyrate Producers

per Elmén, Lisa, Zlamal, Jaime E., Scott, David A., Lee, Ryan B., Chen, Daniel J., Colas, Alexandre R., Rodionov, Dmitry A., Peterson, Scott N.
Publicat a Front Microbiol (2020)

An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes

per McKeithan, Wesley L., Savchenko, Alex, Yu, Michael S., Cerignoli, Fabio, Bruyneel, Arne A. N., Price, Jeffery H., Colas, Alexandre R., Miller, Evan W., Cashman, John R., Mercola, Mark
Publicat a Front Physiol (2017)

Silencing of CCR4-NOT complex subunits affects heart structure and function

per Elmén, Lisa, Volpato, Claudia B., Kervadec, Anaïs, Pineda, Santiago, Kalvakuri, Sreehari, Alayari, Nakissa N., Foco, Luisa, Pramstaller, Peter P., Ocorr, Karen, Rossini, Alessandra, Cammarato, Anthony, Colas, Alexandre R., Hicks, Andrew A., Bodmer, Rolf
Publicat a Dis Model Mech (2020)

PGC1/PPAR drive cardiomyocyte maturation at single cell level via YAP1 and SF3B2

per Murphy, Sean A., Miyamoto, Matthew, Kervadec, Anaïs, Kannan, Suraj, Tampakakis, Emmanouil, Kambhampati, Sandeep, Lin, Brian Leei, Paek, Sam, Andersen, Peter, Lee, Dong-Ik, Zhu, Renjun, An, Steven S., Kass, David A., Uosaki, Hideki, Colas, Alexandre R., Kwon, Chulan
Publicat a Nat Commun (2021)

Model system identification of novel congenital heart disease gene candidates: focus on RPL13

per Schroeder, Analyne M, Allahyari, Massoud, Vogler, Georg, Missinato, Maria A, Nielsen, Tanja, Yu, Michael S, Theis, Jeanne L, Larsen, Lars A, Goyal, Preeya, Rosenfeld, Jill A, Nelson, Timothy J, Olson, Timothy M, Colas, Alexandre R, Grossfeld, Paul, Bodmer, Rolf
Publicat a Hum Mol Genet (2019)

Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation

per Salomonis, Nathan, Schlieve, Christopher R., Pereira, Laura, Wahlquist, Christine, Colas, Alexandre, Zambon, Alexander C., Vranizan, Karen, Spindler, Matthew J., Pico, Alexander R., Cline, Melissa S., Clark, Tyson A., Williams, Alan, Blume, John E., Samal, Eva, Mercola, Mark, Merrill, Bradley J., Conklin, Bruce R.
Publicat 2010

Id genes are essential for early heart formation

per Cunningham, Thomas J., Yu, Michael S., McKeithan, Wesley L., Spiering, Sean, Carrette, Florent, Huang, Chun-Teng, Bushway, Paul J., Tierney, Matthew, Albini, Sonia, Giacca, Mauro, Mano, Miguel, Puri, Pier Lorenzo, Sacco, Alessandra, Ruiz-Lozano, Pilar, Riou, Jean-Francois, Umbhauer, Muriel, Duester, Gregg, Mercola, Mark, Colas, Alexandre R.
Publicat a Genes Dev (2017)

Acellular therapeutic approach for heart failure: in vitro production of extracellular vesicles from human cardiovascular progenitors

per El Harane, Nadia, Kervadec, Anaïs, Bellamy, Valérie, Pidial, Laetitia, Neametalla, Hany J, Perier, Marie-Cécile, Lima Correa, Bruna, Thiébault, Léa, Cagnard, Nicolas, Duché, Angéline, Brunaud, Camille, Lemitre, Mathilde, Gauthier, Jeanne, Bourdillon, Alexandra T, Renault, Marc P, Hovhannisyan, Yeranuhi, Paiva, Solenne, Colas, Alexandre R, Agbulut, Onnik, Hagège, Albert, Silvestre, Jean-Sébastien, Menasché, Philippe, Renault, Nisa K E
Publicat a Eur Heart J (2018)

Small Molecule Probe Reveals a Kinase Cascade that Links Stress Signaling to TCF/LEF and Wnt Responsiveness

per Cheng, Jiongjia, Tsuda, Masanao, Okolotowicz, Karl, Dwyer, Mary, Bushway, Paul J., Colas, Alexandre R., Lancman, Joseph J., Schade, Dennis, Perea-Gil, Isaac, Bruyneel, Arne A.N., Lee, Jaechol, Vadgama, Nirmal, Quach, Justine, McKeithan, Wesley L., Biechele, Travis L., Wu, Joseph C., Moon, Randall T., Si Dong, P. Duc, Karakikes, Ioannis, Cashman, John R., Mercola, Mark
Publicat a Cell Chem Biol (2021)

Patient-specific genomics and cross-species functional analysis implicate LRP2 in hypoplastic left heart syndrome

per Theis, Jeanne L, Vogler, Georg, Missinato, Maria A, Li, Xing, Nielsen, Tanja, Zeng, Xin-Xin I, Martinez-Fernandez, Almudena, Walls, Stanley M, Kervadec, Anaïs, Kezos, James N, Birker, Katja, Evans, Jared M, O'Byrne, Megan M, Fogarty, Zachary C, Terzic, André, Grossfeld, Paul, Ocorr, Karen, Nelson, Timothy J, Olson, Timothy M, Colas, Alexandre R, Bodmer, Rolf
Publicat a eLife (2020)