Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation

Two major goals of regenerative medicine are to reproducibly transform adult somatic cells into a pluripotent state and to control their differentiation into specific cell fates. Progress toward these goals would be greatly helped by obtaining a complete picture of the RNA isoforms produced by these...

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Main Authors: Salomonis, Nathan, Schlieve, Christopher R., Pereira, Laura, Wahlquist, Christine, Colas, Alexandre, Zambon, Alexander C., Vranizan, Karen, Spindler, Matthew J., Pico, Alexander R., Cline, Melissa S., Clark, Tyson A., Williams, Alan, Blume, John E., Samal, Eva, Mercola, Mark, Merrill, Bradley J., Conklin, Bruce R.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890851/
https://ncbi.nlm.nih.gov/pubmed/20498046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912260107
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