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Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis

Tight control over the segregation of endoderm, mesoderm, and ectoderm is essential for normal embryonic development of all species, yet how neighboring embryonic blastomeres can contribute to different germ layers has never been fully explained. We postulated that microRNAs, which fine-tune many bi...

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Detalhes bibliográficos
Main Authors: Colas, Alexandre R., McKeithan, Wesley L., Cunningham, Thomas J., Bushway, Paul J., Garmire, Lana X., Duester, Gregg, Subramaniam, Shankar, Mercola, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3521625/
https://ncbi.nlm.nih.gov/pubmed/23152446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.200758.112
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