Identification and molecular basis for SIRT6 loss-of-function point mutations in cancer

Por Kugel, Sita, Feldman, Jessica L., Klein, Mark A., Silberman, Dafne M., Sebastián, Carlos, Mermel, Craig, Dobersch, Stephanie, Clark, Abbe R., Getz, Gad, Denu, John M., Mostoslavsky, Raul
Publicado no Cell Rep (2015)

Inducible podocyte-specific deletion of CTCF drives progressive kidney disease and bone abnormalities

Por Christov, Marta, Clark, Abbe R., Corbin, Braden, Hakroush, Samy, Rhee, Eugene P., Saito, Hiroaki, Brooks, Dan, Hesse, Eric, Bouxsein, Mary, Galjart, Niels, Jung, Ji Yong, Mundel, Peter, Jüppner, Harald, Weins, Astrid, Greka, Anna
Publicado no JCI Insight (2018)

A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models

Por Zhou, Yiming, Castonguay, Philip, Sidhom, Eriene-Heidi, Clark, Abbe R., Dvela-Levitt, Moran, Kim, Sookyung, Sieber, Jonas, Wieder, Nicolas, Jung, Ji Yong, Andreeva, Svetlana, Reichardt, Jana, Dubois, Frank, Hoffmann, Sigrid C., Basgen, John M., MontesinoS, Mónica S., Weins, Astrid, Johnson, Ashley C., Lander, Eric S., Garrett, Michael R., Hopkins, Corey R., Greka, Anna
Publicado no Science (2017)

A High-Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury

Por Kost-Alimova, Maria, Sidhom, Eriene-Heidi, Satyam, Abhigyan, Chamberlain, Brian T., Dvela-Levitt, Moran, Melanson, Michelle, Alper, Seth L., Santos, Jean, Gutierrez, Juan, Subramanian, Ayshwarya, Byrne, Patrick J., Grinkevich, Elizabeth, Reyes-Bricio, Estefanía, Kim, Choah, Clark, Abbe R., Watts, Andrew J.B., Thompson, Rebecca, Marshall, Jamie, Pablo, Juan Lorenzo, Coraor, Juliana, Roignot, Julie, Vernon, Katherine A., Keller, Keith, Campbell, Alissa, Emani, Maheswarareddy, Racette, Matthew, Bazua-Valenti, Silvana, Padovano, Valeria, Weins, Astrid, McAdoo, Stephen P., Tam, Frederick W.K., Ronco, Luciene, Wagner, Florence, Tsokos, George C., Shaw, Jillian L., Greka, Anna
Publicado no Cell Rep Med (2020)