Arachidonic acid mediates the formation of abundant alpha-helical multimers of alpha-synuclein

Por Iljina, Marija, Tosatto, Laura, Choi, Minee L., Sang, Jason C., Ye, Yu, Hughes, Craig D., Bryant, Clare E., Gandhi, Sonia, Klenerman, David
Publicado no Sci Rep (2016)

Kinetic model of the aggregation of alpha-synuclein provides insights into prion-like spreading

Por Iljina, Marija, Garcia, Gonzalo A., Horrocks, Mathew H., Tosatto, Laura, Choi, Minee L., Ganzinger, Kristina A., Abramov, Andrey Y., Gandhi, Sonia, Wood, Nicholas W., Cremades, Nunilo, Dobson, Christopher M., Knowles, Tuomas P. J., Klenerman, David
Publicado no Proc Natl Acad Sci U S A (2016)

Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species

Por Iljina, Marija, Hong, Liu, Horrocks, Mathew H., Ludtmann, Marthe H., Choi, Minee L., Hughes, Craig D., Ruggeri, Francesco S., Guilliams, Tim, Buell, Alexander K., Lee, Ji-Eun, Gandhi, Sonia, Lee, Steven F., Bryant, Clare E., Vendruscolo, Michele, Knowles, Tuomas P. J., Dobson, Christopher M., De Genst, Erwin, Klenerman, David
Publicado no BMC Biol (2017)

Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS

Por Hall, Claire E., Yao, Zhi, Choi, Minee, Tyzack, Giulia E., Serio, Andrea, Luisier, Raphaelle, Harley, Jasmine, Preza, Elisavet, Arber, Charlie, Crisp, Sarah J., Watson, P. Marc D., Kullmann, Dimitri M., Abramov, Andrey Y., Wray, Selina, Burley, Russell, Loh, Samantha H.Y., Martins, L. Miguel, Stevens, Molly M., Luscombe, Nicholas M., Sibley, Christopher R., Lakatos, Andras, Ule, Jernej, Gandhi, Sonia, Patani, Rickie
Publicado no Cell Rep (2017)

α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease

Por Ludtmann, Marthe H. R., Angelova, Plamena R., Horrocks, Mathew H., Choi, Minee L., Rodrigues, Margarida, Baev, Artyom Y., Berezhnov, Alexey V., Yao, Zhi, Little, Daniel, Banushi, Blerida, Al-Menhali, Afnan Saleh, Ranasinghe, Rohan T., Whiten, Daniel R., Yapom, Ratsuda, Dolt, Karamjit Singh, Devine, Michael J., Gissen, Paul, Kunath, Tilo, Jaganjac, Morana, Pavlov, Evgeny V., Klenerman, David, Abramov, Andrey Y., Gandhi, Sonia
Publicado no Nat Commun (2018)