A comprehensive characterization of cis-acting splicing-associated variants in human cancer

door Shiraishi, Yuichi, Kataoka, Keisuke, Chiba, Kenichi, Okada, Ai, Kogure, Yasunori, Tanaka, Hiroko, Ogawa, Seishi, Miyano, Satoru
Gepubliceerd in Genome Res (2018)

Molecular studies reveal MLL-MLLT10/AF10 and ARID5B-MLL gene fusions displaced in a case of infantile acute lymphoblastic leukemia with complex karyotype

door Hiwatari, Mitsuteru, Seki, Masafumi, Akahoshi, Shogo, Yoshida, Kenichi, Miyano, Satoru, Shiraishi, Yuichi, Tanaka, Hiroko, Chiba, Kenichi, Ogawa, Seishi, Takita, Junko
Gepubliceerd in Oncol Lett (2017)

An empirical Bayesian framework for somatic mutation detection from cancer genome sequencing data

door Shiraishi, Yuichi, Sato, Yusuke, Chiba, Kenichi, Okuno, Yusuke, Nagata, Yasunobu, Yoshida, Kenichi, Shiba, Norio, Hayashi, Yasuhide, Kume, Haruki, Homma, Yukio, Sanada, Masashi, Ogawa, Seishi, Miyano, Satoru
Gepubliceerd in 2013

Variant ALDH2 is associated with accelerated progression of bone marrow failure in Japanese Fanconi anemia patients

door Hira, Asuka, Yabe, Hiromasa, Yoshida, Kenichi, Okuno, Yusuke, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Miyano, Satoru, Nakamura, Jun, Kojima, Seiji, Ogawa, Seishi, Matsuo, Keitaro, Takata, Minoru, Yabe, Miharu
Gepubliceerd in 2013

Mutations in the Gene Encoding the E2 Conjugating Enzyme UBE2T Cause Fanconi Anemia

door Hira, Asuka, Yoshida, Kenichi, Sato, Koichi, Okuno, Yusuke, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Miyano, Satoru, Shimamoto, Akira, Tahara, Hidetoshi, Ito, Etsuro, Kojima, Seiji, Kurumizaka, Hitoshi, Ogawa, Seishi, Takata, Minoru, Yabe, Hiromasa, Yabe, Miharu
Gepubliceerd in Am J Hum Genet (2015)

VAV1 mutations contribute to development of T-cell neoplasms in mice

door Fukumoto, Kota, Sakata-Yanagimoto, Mamiko, Fujisawa, Manabu, Sakamoto, Tatsuhiro, Miyoshi, Hiroaki, Suehara, Yasuhito, Nguyen, Tran B., Suma, Sakurako, Yanagimoto, Shintaro, Shiraishi, Yuichi, Chiba, Kenichi, Bouska, Alyssa, Kataoka, Keisuke, Ogawa, Seishi, Iqbal, Javeed, Ohshima, Koichi, Chiba, Shigeru
Gepubliceerd in Blood (2020)

Somatic mutations in plasma cell-free DNA are diagnostic markers for esophageal squamous cell carcinoma recurrence

door Ueda, Masami, Iguchi, Tomohiro, Masuda, Takaaki, Nakahara, Yujiro, Hirata, Hidenari, Uchi, Ryutaro, Niida, Atsushi, Momose, Kota, Sakimura, Shotaro, Chiba, Kenichi, Eguchi, Hidetoshi, Ito, Shuhei, Sugimachi, Keishi, Yamasaki, Makoto, Suzuki, Yutaka, Miyano, Satoru, Doki, Yuichiro, Mori, Masaki, Mimori, Koshi
Gepubliceerd in Oncotarget (2016)

Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasia

door Shiozawa, Yusuke, Malcovati, Luca, Gallì, Anna, Sato-Otsubo, Aiko, Kataoka, Keisuke, Sato, Yusuke, Watatani, Yosaku, Suzuki, Hiromichi, Yoshizato, Tetsuichi, Yoshida, Kenichi, Sanada, Masashi, Makishima, Hideki, Shiraishi, Yuichi, Chiba, Kenichi, Hellström-Lindberg, Eva, Miyano, Satoru, Ogawa, Seishi, Cazzola, Mario
Gepubliceerd in Nat Commun (2018)

ACTN1 Mutations Cause Congenital Macrothrombocytopenia

door Kunishima, Shinji, Okuno, Yusuke, Yoshida, Kenichi, Shiraishi, Yuichi, Sanada, Masashi, Muramatsu, Hideki, Chiba, Kenichi, Tanaka, Hiroko, Miyazaki, Koji, Sakai, Michio, Ohtake, Masatoshi, Kobayashi, Ryoji, Iguchi, Akihiro, Niimi, Gen, Otsu, Makoto, Takahashi, Yoshiyuki, Miyano, Satoru, Saito, Hidehiko, Kojima, Seiji, Ogawa, Seishi
Gepubliceerd in 2013

Novel neuroblastoma amplified sequence (NBAS) mutations in a Japanese boy with fever-triggered recurrent acute liver failure

door Ono, Sahoko, Matsuda, Junko, Watanabe, Etsuko, Akaike, Hiroto, Teranishi, Hideto, Miyata, Ippei, Otomo, Takanobu, Sadahira, Yoshito, Mizuochi, Tatsuki, Kusano, Hironori, Kage, Masayoshi, Ueno, Hiroo, Yoshida, Kenichi, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Miyano, Satoru, Ogawa, Seishi, Hayashi, Yasuhide, Kanegane, Hirokazu, Ouchi, Kazunobu
Gepubliceerd in Hum Genome Var (2019)

Clonally related diffuse large B-cell lymphoma and interdigitating dendritic cell sarcoma sharing MYC translocation

door Ochi, Yotaro, Hiramoto, Nobuhiro, Yoshizato, Tetsuichi, Ono, Yuichiro, Takeda, June, Shiozawa, Yusuke, Yoshida, Kenichi, Kakiuchi, Nobuyuki, Shiraishi, Yuichi, Tanaka, Hiroko, Chiba, Kenichi, Kazuma, Yasuhiro, Tabata, Sumie, Yonetani, Noboru, Uehara, Keiichiro, Yamashita, Daisuke, Imai, Yukihiro, Nagafuji, Koji, Yamakawa, Mitsunori, Miyano, Satoru, Takaori-Kondo, Akifumi, Ogawa, Seishi, Ishikawa, Takayuki
Gepubliceerd in Haematologica (2018)

Clonal leukemic evolution in myelodysplastic syndromes with TET2 and IDH1/2 mutations

door Lin, Tung-Liang, Nagata, Yasunobu, Kao, Hsiao-Wen, Sanada, Masashi, Okuno, Yusuke, Huang, Chein-Fuang, Liang, Der-Cherng, Kuo, Ming-Chung, Lai, Chang-Liang, Lee, En-Hui, Shih, Yu-Shu, Tanaka, Hiroko, Shiraishi, Yuichi, Chiba, Kenichi, Lin, Tung-Huei, Wu, Jin-Hou, Miyano, Satoru, Ogawa, Seishi, Shih, Lee-Yung
Gepubliceerd in 2014

GATA2 and secondary mutations in familial myelodysplastic syndromes and pediatric myeloid malignancies

door Wang, Xinan, Muramatsu, Hideki, Okuno, Yusuke, Sakaguchi, Hirotoshi, Yoshida, Kenichi, Kawashima, Nozomu, Xu, Yinyan, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Saito, Shoji, Nakazawa, Yozo, Masunari, Taro, Hirose, Tadashi, Elmahdi, Shaimaa, Narita, Atsushi, Doisaki, Sayoko, Ismael, Olfat, Makishima, Hideki, Hama, Asahito, Miyano, Satoru, Takahashi, Yoshiyuki, Ogawa, Seishi, Kojima, Seiji
Gepubliceerd in Haematologica (2015)

Comprehensive genetic analysis of pediatric germ cell tumors identifies potential drug targets

door Kubota, Yasuo, Seki, Masafumi, Kawai, Tomoko, Isobe, Tomoya, Yoshida, Misa, Sekiguchi, Masahiro, Kimura, Shunsuke, Watanabe, Kentaro, Sato-Otsubo, Aiko, Yoshida, Kenichi, Suzuki, Hiromichi, Kataoka, Keisuke, Fujii, Yoichi, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Hiwatari, Mitsuteru, Oka, Akira, Hayashi, Yasuhide, Miyano, Satoru, Ogawa, Seishi, Hata, Kenichiro, Tanaka, Yukichi, Takita, Junko
Gepubliceerd in Commun Biol (2020)

Fusion partner–specific mutation profiles and KRAS mutations as adverse prognostic factors in MLL-rearranged AML

door Matsuo, Hidemasa, Yoshida, Kenichi, Nakatani, Kana, Harata, Yutarou, Higashitani, Moe, Ito, Yuri, Kamikubo, Yasuhiko, Shiozawa, Yusuke, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Okada, Ai, Nannya, Yasuhito, Takeda, June, Ueno, Hiroo, Kiyokawa, Nobutaka, Tomizawa, Daisuke, Taga, Takashi, Tawa, Akio, Miyano, Satoru, Meggendorfer, Manja, Haferlach, Claudia, Ogawa, Seishi, Adachi, Souichi
Gepubliceerd in Blood Adv (2020)

Transcriptome analysis offers a comprehensive illustration of the genetic background of pediatric acute myeloid leukemia

door Shiba, Norio, Yoshida, Kenichi, Hara, Yusuke, Yamato, Genki, Shiraishi, Yuichi, Matsuo, Hidemasa, Okuno, Yusuke, Chiba, Kenichi, Tanaka, Hiroko, Kaburagi, Taeko, Takeuchi, Masanobu, Ohki, Kentaro, Sanada, Masashi, Okubo, Jun, Tomizawa, Daisuke, Taki, Tomohiko, Shimada, Akira, Sotomatsu, Manabu, Horibe, Keizo, Taga, Takashi, Adachi, Souichi, Tawa, Akio, Miyano, Satoru, Ogawa, Seishi, Hayashi, Yasuhide
Gepubliceerd in Blood Adv (2019)

Exome sequencing identified RPS15A as a novel causative gene for Diamond-Blackfan anemia

door Ikeda, Fumika, Yoshida, Kenichi, Toki, Tsutomu, Uechi, Tamayo, Ishida, Shiori, Nakajima, Yukari, Sasahara, Yoji, Okuno, Yusuke, Kanezaki, Rika, Terui, Kiminori, Kamio, Takuya, Kobayashi, Akie, Fujita, Takashi, Sato-Otsubo, Aiko, Shiraishi, Yuichi, Tanaka, Hiroko, Chiba, Kenichi, Muramatsu, Hideki, Kanno, Hitoshi, Ohga, Shouichi, Ohara, Akira, Kojima, Seiji, Kenmochi, Naoya, Miyano, Satoru, Ogawa, Seishi, Ito, Etsuro
Gepubliceerd in Haematologica (2017)

Identification of the genetic and clinical characteristics of neuroblastomas using genome-wide analysis

door Uryu, Kumiko, Nishimura, Riki, Kataoka, Keisuke, Sato, Yusuke, Nakazawa, Atsuko, Suzuki, Hiromichi, Yoshida, Kenichi, Seki, Masafumi, Hiwatari, Mitsuteru, Isobe, Tomoya, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Miyano, Satoru, Koh, Katsuyoshi, Hanada, Ryoji, Oka, Akira, Hayashi, Yasuhide, Ohira, Miki, Kamijo, Takehiko, Nagase, Hiroki, Takimoto, Tetsuya, Tajiri, Tatsuro, Nakagawara, Akira, Ogawa, Seishi, Takita, Junko
Gepubliceerd in Oncotarget (2017)

Frequent germline mutations of HAVCR2 in sporadic subcutaneous panniculitis-like T-cell lymphoma

door Polprasert, Chantana, Takeuchi, Yasuhide, Kakiuchi, Nobuyuki, Yoshida, Kenichi, Assanasen, Thamathorn, Sitthi, Wimonmas, Bunworasate, Udomsak, Pirunsarn, Arunrat, Wudhikarn, Kitsada, Lawasut, Panisinee, Uaprasert, Noppacharn, Kongkiatkamon, Sunisa, Moonla, Chatphatai, Sanada, Masashi, Akita, Nobuhiro, Takeda, June, Fujii, Yoichi, Suzuki, Hiromichi, Nannya, Yasuhito, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Miyano, Satoru, Rojnuckarin, Ponlapat, Ogawa, Seishi, Makishima, Hideki
Gepubliceerd in Blood Adv (2019)

Integrated genetic and epigenetic analysis revealed heterogeneity of acute lymphoblastic leukemia in Down syndrome

door Kubota, Yasuo, Uryu, Kumiko, Ito, Tatsuya, Seki, Masafumi, Kawai, Tomoko, Isobe, Tomoya, Kumagai, Tadayuki, Toki, Tsutomu, Yoshida, Kenichi, Suzuki, Hiromichi, Kataoka, Keisuke, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Ohki, Kentaro, Kiyokawa, Nobutaka, Kagawa, Jiro, Miyano, Satoru, Oka, Akira, Hayashi, Yasuhide, Ogawa, Seishi, Terui, Kiminori, Sato, Atsushi, Hata, Kenichiro, Ito, Etsuro, Takita, Junko
Gepubliceerd in Cancer Sci (2019)