Integrated genetic and epigenetic analysis revealed heterogeneity of acute lymphoblastic leukemia in Down syndrome

Children with Down syndrome (DS) are at a 20‐fold increased risk for acute lymphoblastic leukemia (ALL). Compared to children with ALL and no DS (non‐DS‐ALL), those with DS and ALL (DS‐ALL) harbor uncommon genetic alterations, suggesting DS‐ALL could have distinct biological features. Recent studies...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Kubota, Yasuo, Uryu, Kumiko, Ito, Tatsuya, Seki, Masafumi, Kawai, Tomoko, Isobe, Tomoya, Kumagai, Tadayuki, Toki, Tsutomu, Yoshida, Kenichi, Suzuki, Hiromichi, Kataoka, Keisuke, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Ohki, Kentaro, Kiyokawa, Nobutaka, Kagawa, Jiro, Miyano, Satoru, Oka, Akira, Hayashi, Yasuhide, Ogawa, Seishi, Terui, Kiminori, Sato, Atsushi, Hata, Kenichiro, Ito, Etsuro, Takita, Junko
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778645/
https://ncbi.nlm.nih.gov/pubmed/31385395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14160
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