Integrated genetic and epigenetic analysis revealed heterogeneity of acute lymphoblastic leukemia in Down syndrome

Children with Down syndrome (DS) are at a 20‐fold increased risk for acute lymphoblastic leukemia (ALL). Compared to children with ALL and no DS (non‐DS‐ALL), those with DS and ALL (DS‐ALL) harbor uncommon genetic alterations, suggesting DS‐ALL could have distinct biological features. Recent studies...

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Publicat a:Cancer Sci
Autors principals: Kubota, Yasuo, Uryu, Kumiko, Ito, Tatsuya, Seki, Masafumi, Kawai, Tomoko, Isobe, Tomoya, Kumagai, Tadayuki, Toki, Tsutomu, Yoshida, Kenichi, Suzuki, Hiromichi, Kataoka, Keisuke, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Ohki, Kentaro, Kiyokawa, Nobutaka, Kagawa, Jiro, Miyano, Satoru, Oka, Akira, Hayashi, Yasuhide, Ogawa, Seishi, Terui, Kiminori, Sato, Atsushi, Hata, Kenichiro, Ito, Etsuro, Takita, Junko
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778645/
https://ncbi.nlm.nih.gov/pubmed/31385395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14160
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