Clonal leukemic evolution in myelodysplastic syndromes with TET2 and IDH1/2 mutations

Somatic mutations of TET2, IDH1, and IDH2 have been described in myelodysplastic syndrome. The impact of these mutations on outcome of myelodysplastic syndrome and their progression to secondary acute myeloid leukemia remains unclear. Mutation status of TET2, IDH1 and IDH2 was investigated in a coho...

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Main Authors: Lin, Tung-Liang, Nagata, Yasunobu, Kao, Hsiao-Wen, Sanada, Masashi, Okuno, Yusuke, Huang, Chein-Fuang, Liang, Der-Cherng, Kuo, Ming-Chung, Lai, Chang-Liang, Lee, En-Hui, Shih, Yu-Shu, Tanaka, Hiroko, Shiraishi, Yuichi, Chiba, Kenichi, Lin, Tung-Huei, Wu, Jin-Hou, Miyano, Satoru, Ogawa, Seishi, Shih, Lee-Yung
Format: Artigo
Language:Inglês
Published: Ferrata Storti Foundation 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007920/
https://ncbi.nlm.nih.gov/pubmed/23996483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.091249
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