Combined Pharmacological and Genetic Manipulations Unlock Unprecedented Temporal Elasticity and Reveal Phase-Specific Modulation of the Molecular Circadian Clock of the Mouse Supra...

Por Patton, Andrew P., Chesham, Johanna E., Hastings, Michael H.
Publicado no J Neurosci (2016)

A diversity of paracrine signals sustains molecular circadian cycling in suprachiasmatic nucleus circuits

Por Maywood, Elizabeth S., Chesham, Johanna E., O'Brien, John A., Hastings, Michael H.
Publicado em 2011

cAMP-Dependent Signalling as a Core Component of the Mammalian Circadian Pacemaker

Por O’Neill, John S., Maywood, Elizabeth S., Chesham, Johanna E., Takahashi, Joseph S., Hastings, Michael H.
Publicado em 2008

Rhythmic expression of cryptochrome induces the circadian clock of arrhythmic suprachiasmatic nuclei through arginine vasopressin signaling

Por Edwards, Mathew D., Brancaccio, Marco, Chesham, Johanna E., Maywood, Elizabeth S., Hastings, Michael H.
Publicado no Proc Natl Acad Sci U S A (2016)

Temporally chimeric mice reveal flexibility of circadian period-setting in the suprachiasmatic nucleus

Por Smyllie, Nicola J., Chesham, Johanna E., Hamnett, Ryan, Maywood, Elizabeth S., Hastings, Michael H.
Publicado no Proc Natl Acad Sci U S A (2016)

Astrocytes Control Circadian Timekeeping in the Suprachiasmatic Nucleus via Glutamatergic Signaling

Por Brancaccio, Marco, Patton, Andrew P., Chesham, Johanna E., Maywood, Elizabeth S., Hastings, Michael H.
Publicado no Neuron (2017)

A Gq-Ca(2+) Axis Controls Circuit-Level Encoding of Circadian Time in the Suprachiasmatic Nucleus

Por Brancaccio, Marco, Maywood, Elizabeth S., Chesham, Johanna E., Loudon, Andrew S.I., Hastings, Michael H.
Publicado em 2013

Regulation of alternative splicing by the circadian clock and food related cues

Por McGlincy, Nicholas J, Valomon, Amandine, Chesham, Johanna E, Maywood, Elizabeth S, Hastings, Michael H, Ule, Jernej
Publicado em 2012

Prokineticin receptor 2 (Prokr2) is essential for the regulation of circadian behavior by the suprachiasmatic nuclei

Por Prosser, Haydn M., Bradley, Allan, Chesham, Johanna E., Ebling, Francis J. P., Hastings, Michael H., Maywood, Elizabeth S.
Publicado em 2007

Distinct and Separable Roles for Endogenous CRY1 and CRY2 within the Circadian Molecular Clockwork of the Suprachiasmatic Nucleus, as Revealed by the Fbxl3(Afh) Mutation

Por Anand, Sneha N., Maywood, Elizabeth S., Chesham, Johanna E., Joynson, Greg, Banks, Gareth T., Hastings, Michael H., Nolan, Patrick M.
Publicado em 2013

Early doors (Edo) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking

Por Militi, Stefania, Maywood, Elizabeth S., Sandate, Colby R., Chesham, Johanna E., Barnard, Alun R., Parsons, Michael J., Vibert, Jennifer L., Joynson, Greg M., Partch, Carrie L., Hastings, Michael H., Nolan, Patrick M.
Publicado no Proc Natl Acad Sci U S A (2016)

Analysis of core circadian feedback loop in suprachiasmatic nucleus of mCry1-luc transgenic reporter mouse

Por Maywood, Elizabeth S., Drynan, Lesley, Chesham, Johanna E., Edwards, Mathew D., Dardente, Hugues, Fustin, Jean-Michel, Hazlerigg, David G., O’Neill, John S., Codner, Gemma F., Smyllie, Nicola J., Brancaccio, Marco, Hastings, Michael H.
Publicado em 2013

Circadian Factor BMAL1 in Histaminergic Neurons Regulates Sleep Architecture

Por Yu, Xiao, Zecharia, Anna, Zhang, Zhe, Yang, Qianzi, Yustos, Raquel, Jager, Polona, Vyssotski, Alexei L., Maywood, Elizabeth S., Chesham, Johanna E., Ma, Ying, Brickley, Stephen G., Hastings, Michael H., Franks, Nicholas P., Wisden, William
Publicado no Curr Biol (2014)

Visualizing and Quantifying Intracellular Behavior and Abundance of the Core Circadian Clock Protein PERIOD2

Por Smyllie, Nicola J., Pilorz, Violetta, Boyd, James, Meng, Qing-Jun, Saer, Ben, Chesham, Johanna E., Maywood, Elizabeth S., Krogager, Toke P., Spiller, David G., Boot-Handford, Raymond, White, Michael R.H., Hastings, Michael H., Loudon, Andrew S.I.
Publicado no Curr Biol (2016)

Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes

Por Meng, Qing-Jun, Maywood, Elizabeth S., Bechtold, David A., Lu, Wei-Qun, Li, Jian, Gibbs, Julie E., Dupré, Sandrine M., Chesham, Johanna E., Rajamohan, Francis, Knafels, John, Sneed, Blossom, Zawadzke, Laura E., Ohren, Jeffrey F., Walton, Kevin M., Wager, Travis T., Hastings, Michael H., Loudon, Andrew S. I.
Publicado em 2010

Disrupted Circadian Rhythms in a Mouse Model of Schizophrenia

Por Oliver, Peter L., Sobczyk, Melanie V., Maywood, Elizabeth S., Edwards, Benjamin, Lee, Sheena, Livieratos, Achilleas, Oster, Henrik, Butler, Rachel, Godinho, Sofia I.H., Wulff, Katharina, Peirson, Stuart N., Fisher, Simon P., Chesham, Johanna E., Smith, Janice W., Hastings, Michael H., Davies, Kay E., Foster, Russell G.
Publicado em 2012

Setting clock speed in mammals: the CK1ε tau mutation in mice accelerates the circadian pacemaker by selectively destabilizing PERIOD proteins

Por Meng, Qing-Jun, Logunova, Larisa, Maywood, Elizabeth S., Gallego, Monica, Lebiecki, Jake, Brown, Timothy M., Sládek, Martin, Semikhodskii, Andrei S., Glossop, Nicholas R.J., Piggins, Hugh D., Chesham, Johanna E., Bechtold, David A., Yoo, Seung-Hee, Takahashi, Joseph S, Virshup, David M., Boot-Handford, Raymond P., Hastings, Michael H., Loudon, Andrew S.I.
Publicado em 2008

The Regulatory Factor ZFHX3 Modifies Circadian Function in SCN via an AT Motif-Driven Axis

Por Parsons, Michael J., Brancaccio, Marco, Sethi, Siddharth, Maywood, Elizabeth S., Satija, Rahul, Edwards, Jessica K., Jagannath, Aarti, Couch, Yvonne, Finelli, Mattéa J., Smyllie, Nicola J., Esapa, Christopher, Butler, Rachel, Barnard, Alun R., Chesham, Johanna E., Saito, Shoko, Joynson, Greg, Wells, Sara, Foster, Russell G., Oliver, Peter L., Simon, Michelle M., Mallon, Ann-Marie, Hastings, Michael H., Nolan, Patrick M.
Publicado no Cell (2015)