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Rhythmic expression of cryptochrome induces the circadian clock of arrhythmic suprachiasmatic nuclei through arginine vasopressin signaling

Circadian rhythms in mammals are coordinated by the suprachiasmatic nucleus (SCN). SCN neurons define circadian time using transcriptional/posttranslational feedback loops (TTFL) in which expression of Cryptochrome (Cry) and Period (Per) genes is inhibited by their protein products. Loss of Cry1 and...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Edwards, Mathew D., Brancaccio, Marco, Chesham, Johanna E., Maywood, Elizabeth S., Hastings, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791030/
https://ncbi.nlm.nih.gov/pubmed/26903624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1519044113
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