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Rhythmic expression of cryptochrome induces the circadian clock of arrhythmic suprachiasmatic nuclei through arginine vasopressin signaling
Circadian rhythms in mammals are coordinated by the suprachiasmatic nucleus (SCN). SCN neurons define circadian time using transcriptional/posttranslational feedback loops (TTFL) in which expression of Cryptochrome (Cry) and Period (Per) genes is inhibited by their protein products. Loss of Cry1 and...
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Wydane w: | Proc Natl Acad Sci U S A |
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Główni autorzy: | , , , , |
Format: | Artigo |
Język: | Inglês |
Wydane: |
National Academy of Sciences
2016
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4791030/ https://ncbi.nlm.nih.gov/pubmed/26903624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1519044113 |
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