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Rhythmic expression of cryptochrome induces the circadian clock of arrhythmic suprachiasmatic nuclei through arginine vasopressin signaling

Circadian rhythms in mammals are coordinated by the suprachiasmatic nucleus (SCN). SCN neurons define circadian time using transcriptional/posttranslational feedback loops (TTFL) in which expression of Cryptochrome (Cry) and Period (Per) genes is inhibited by their protein products. Loss of Cry1 and...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Edwards, Mathew D., Brancaccio, Marco, Chesham, Johanna E., Maywood, Elizabeth S., Hastings, Michael H.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791030/
https://ncbi.nlm.nih.gov/pubmed/26903624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1519044113
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