Antroquinonol Lowers Brain Amyloid-β Levels and Improves Spatial Learning and Memory in a Transgenic Mouse Model of Alzheimer’s Disease

per Chang, Wen-Han, Chen, Miles C., Cheng, Irene H.
Publicat a Sci Rep (2015)

Distinct Effects of Zn(2+), Cu(2+), Fe(3+), and Al(3+) on Amyloid-β Stability, Oligomerization, and Aggregation: AMYLOID-β DESTABILIZATION PROMOTES ANNULAR PROTOFIBRIL FORMATION

per Chen, Wei-Ting, Liao, Yi-Hung, Yu, Hui-Ming, Cheng, Irene H., Chen, Yun-Ru
Publicat 2011

Curcuminoid submicron particle ameliorates cognitive deficits and decreases amyloid pathology in Alzheimer’s disease mouse model

per Tai, Yi-Heng, Lin, Yu-Yi, Wang, Kai-Chen, Chang, Chao-Lin, Chen, Ru-Yin, Wu, Chia-Chu, Cheng, Irene H.
Publicat a Oncotarget (2018)

Plasma Aβ42 and Total Tau Predict Cognitive Decline in Amnestic Mild Cognitive Impairment

per Chen, Ting-Bin, Lee, Yi-Jung, Lin, Szu-Ying, Chen, Jun-Peng, Hu, Chaur-Jong, Wang, Pei-Ning, Cheng, Irene H.
Publicat a Sci Rep (2019)

Neprilysin Overexpression Inhibits Plaque Formation But Fails to Reduce Pathogenic Aβ Oligomers and Associated Cognitive Deficits in Human Amyloid Precursor Protein Transgenic Mice...

per Meilandt, William J., Cisse, Moustapha, Ho, Kaitlyn, Wu, Tiffany, Esposito, Luke A., Scearce-Levie, Kimberly, Cheng, Irene H., Yu, Gui-Qiu, Mucke, Lennart
Publicat 2009

Collagen VI protects neurons against Aβ toxicity

per Cheng, Jason S, Dubal, Dena B, Kim, Daniel H, Legleiter, Justin, Cheng, Irene H, Yu, Gui-Qiu, Tesseur, Ina, Wyss-Coray, Tony, Bonaldo, Paolo, Mucke, Lennart
Publicat 2009

Acid-Sensing Ion Channel-1a Is Not Required for Normal Hippocampal LTP and Spatial Memory

per Wu, Pu-Yeh, Huang, Yu-Yin, Chen, Chien-Chun, Hsu, Tsan-Ting, Lin, Yen-Chu, Weng, Ju-Yun, Chien, Ta-Chun, Cheng, Irene H, Lien, Cheng-Chang
Publicat a J Neurosci (2013)

Phospholipase A(2) reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease

per Sanchez-Mejia, Rene O., Newman, John W., Toh, Sandy, Yu, Gui-Qiu, Zhou, Yungui, Halabisky, Brian, Cissé, Moustapha, Scearce-Levie, Kimberly, Cheng, Irene H., Gan, Li, Palop, Jorge J., Bonventre, Joseph V., Mucke, Lennart
Publicat 2008

Amyloid-Beta (Aβ) D7H Mutation Increases Oligomeric Aβ42 and Alters Properties of Aβ-Zinc/Copper Assemblies

per Chen, Wei-Ting, Hong, Chen-Jee, Lin, Ya-Tzu, Chang, Wen-Han, Huang, He-Ting, Liao, Jhih-Ying, Chang, Yu-Jen, Hsieh, Yi-Fang, Cheng, Chih-Ya, Liu, Hsiu-Chih, Chen, Yun-Ru, Cheng, Irene H.
Publicat 2012

ENU Mutagenesis Identifies Mice with Morbid Obesity and Severe Hyperinsulinemia Caused by a Novel Mutation in Leptin

per Hong, Chen-Jee, Tsai, Pei-Jane, Cheng, Chih-Ya, Chou, Chuan-Kai, Jheng, Huei-Fen, Chuang, You-Chung, Yang, Chia-Ning, Lin, Ya-Tzu, Hsu, Chih-Wei, Cheng, Irene H., Chen, Shiow-Yi, Tsai, Shih-Jen, Liou, Ying-Jay, Tsai, Yau-Sheng
Publicat 2010