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Collagen VI protects neurons against Aβ toxicity
Amyloid-β (Aβ) peptides, widely presumed to cause Alzheimer’s disease, increased mouse neuronal expression of collagen VI through a mechanism involving transforming growth factor signaling. Reduction of collagen VI augmented Aβ neurotoxicity, whereas treatment of neurons with soluble collagen VI blo...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2812922/ https://ncbi.nlm.nih.gov/pubmed/19122666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2240 |
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