Antroquinonol Lowers Brain Amyloid-β Levels and Improves Spatial Learning and Memory in a Transgenic Mouse Model of Alzheimer’s Disease

Por Chang, Wen-Han, Chen, Miles C., Cheng, Irene H.
Publicado no Sci Rep (2015)

Distinct Effects of Zn(2+), Cu(2+), Fe(3+), and Al(3+) on Amyloid-β Stability, Oligomerization, and Aggregation: AMYLOID-β DESTABILIZATION PROMOTES ANNULAR PROTOFIBRIL FORMATION

Por Chen, Wei-Ting, Liao, Yi-Hung, Yu, Hui-Ming, Cheng, Irene H., Chen, Yun-Ru
Publicado em 2011

Curcuminoid submicron particle ameliorates cognitive deficits and decreases amyloid pathology in Alzheimer’s disease mouse model

Por Tai, Yi-Heng, Lin, Yu-Yi, Wang, Kai-Chen, Chang, Chao-Lin, Chen, Ru-Yin, Wu, Chia-Chu, Cheng, Irene H.
Publicado no Oncotarget (2018)

Neprilysin Overexpression Inhibits Plaque Formation But Fails to Reduce Pathogenic Aβ Oligomers and Associated Cognitive Deficits in Human Amyloid Precursor Protein Transgenic Mice...

Por Meilandt, William J., Cisse, Moustapha, Ho, Kaitlyn, Wu, Tiffany, Esposito, Luke A., Scearce-Levie, Kimberly, Cheng, Irene H., Yu, Gui-Qiu, Mucke, Lennart
Publicado em 2009

Collagen VI protects neurons against Aβ toxicity

Por Cheng, Jason S, Dubal, Dena B, Kim, Daniel H, Legleiter, Justin, Cheng, Irene H, Yu, Gui-Qiu, Tesseur, Ina, Wyss-Coray, Tony, Bonaldo, Paolo, Mucke, Lennart
Publicado em 2009

Phospholipase A(2) reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease

Por Sanchez-Mejia, Rene O., Newman, John W., Toh, Sandy, Yu, Gui-Qiu, Zhou, Yungui, Halabisky, Brian, Cissé, Moustapha, Scearce-Levie, Kimberly, Cheng, Irene H., Gan, Li, Palop, Jorge J., Bonventre, Joseph V., Mucke, Lennart
Publicado em 2008

Amyloid-Beta (Aβ) D7H Mutation Increases Oligomeric Aβ42 and Alters Properties of Aβ-Zinc/Copper Assemblies

Por Chen, Wei-Ting, Hong, Chen-Jee, Lin, Ya-Tzu, Chang, Wen-Han, Huang, He-Ting, Liao, Jhih-Ying, Chang, Yu-Jen, Hsieh, Yi-Fang, Cheng, Chih-Ya, Liu, Hsiu-Chih, Chen, Yun-Ru, Cheng, Irene H.
Publicado em 2012

ENU Mutagenesis Identifies Mice with Morbid Obesity and Severe Hyperinsulinemia Caused by a Novel Mutation in Leptin

Por Hong, Chen-Jee, Tsai, Pei-Jane, Cheng, Chih-Ya, Chou, Chuan-Kai, Jheng, Huei-Fen, Chuang, You-Chung, Yang, Chia-Ning, Lin, Ya-Tzu, Hsu, Chih-Wei, Cheng, Irene H., Chen, Shiow-Yi, Tsai, Shih-Jen, Liou, Ying-Jay, Tsai, Yau-Sheng
Publicado em 2010