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Annexin A2 mediates secretion of collagen VI, pulmonary elasticity and apoptosis of bronchial epithelial cells

The annexins are an evolutionarily conserved family of phospholipid-binding proteins of largely unknown function. We observed that the AnxA2(−/−) lung basement membrane specifically lacks collagen VI (COL6), and postulated that ANXA2 directs bronchial epithelial cell secretion of COL6, an unusually...

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Detalhes bibliográficos
Main Authors: Dassah, MaryAnn, Almeida, Dena, Hahn, Rebecca, Bonaldo, Paolo, Worgall, Stefan, Hajjar, Katherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924203/
https://ncbi.nlm.nih.gov/pubmed/24357721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.137802
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