Himbacine-Derived Thrombin Receptor Antagonists: C(7)-Aminomethyl and C(9a)-Hydroxy Analogues of Vorapaxar

por Chelliah, Mariappan V., Chackalamannil, Samuel, Xia, Yan, Greenlee, William J., Ahn, Ho-Sam, Kurowski, Stan, Boykow, George, Hsieh, Yunsheng, Chintala, Madhu
Publicado 2013

Himbacine-Derived Thrombin Receptor Antagonists: C(7)-Spirocyclic Analogues of Vorapaxar

por Chelliah, Mariappan V., Eagen, Keith, Guo, Zhuyan, Chackalamannil, Samuel, Xia, Yan, Tsai, Hsingan, Greenlee, William J., Ahn, Ho-Sam, Kurowski, Stan, Boykow, George, Hsieh, Yunsheng, Chintala, Madhu
Publicado 2014

Design, Synthesis, and Evaluation of Novel and Selective G-protein Coupled Receptor 120 (GPR120) Spirocyclic Agonists

por Cox, Jason M., Chu, Hong D., Chelliah, Mariappan V., Debenham, John S., Eagen, Keith, Lan, Ping, Lombardo, Matthew, London, Clare, Plotkin, Michael A., Shah, Unmesh, Sun, Zhongxiang, Vaccaro, Henry M., Venkatraman, Srikanth, Suzuki, Takao, Wang, Nengxue, Ashley, Eric R., Crespo, Alejandro, Madeira, Maria, Leung, Dennis H., Alleyne, Candice, Ogawa, Aimie M., Souza, Sarah, Thomas-Fowlkes, Brande, Di Salvo, Jerry, Weinglass, Adam, Kirkland, Melissa, Pachanski, Michele, Powles, Mary Ann, Tozzo, Effie, Akiyama, Taro E., Ujjainwalla, Feroze, Tata, James R., Sinz, Christopher J.
Publicado en ACS Med Chem Lett (2016)