The utility of animal models to evaluate novel anti-obesity agents

Por Vickers, Steven P, Jackson, Helen C, Cheetham, Sharon C
Publicado em 2011

Combination of the sodium-glucose cotransporter-2 inhibitor empagliflozin with orlistat or sibutramine further improves the body-weight reduction and glucose homeostasis of obese r...

Por Vickers, Steven P, Cheetham, Sharon C, Headland, Katie R, Dickinson, Keith, Grempler, Rolf, Mayoux, Eric, Mark, Michael, Klein, Thomas
Publicado em 2014

Some cannabinoid receptor ligands and their distomers are direct-acting openers of SUR1 K(ATP) channels

Por Lynch, Christopher J., Zhou, Qing, Shyng, Show-Ling, Heal, David J., Cheetham, Sharon C., Dickinson, Keith, Gregory, Peter, Firnges, Michael, Nordheim, Ulrich, Goshorn, Stephanie, Reiche, Dania, Turski, Lechoslaw, Antel, Jochen
Publicado em 2012

Novel, non-nitrocatechol catechol-O-methyltransferase inhibitors modulate dopamine neurotransmission in the frontal cortex and improve cognitive flexibility

Por Byers, Spencer, Buchler, Ingrid P., DePasquale, Michael, Rowley, Helen L., Kulkarni, Rajiv S., Pinder, Lucy, Kolobova, Anna, Li, Cailian, Au, Vinh, Akuma, Daniel, Zhang, Gongliang, Wei, Huijun, Cheetham, Sharon C., Barrow, James C., Carr, Gregory V.
Publicado no Psychopharmacology (Berl) (2020)

Discovery of Highly Selective Inhibitors of Calmodulin-Dependent Kinases That Restore Insulin Sensitivity in the Diet-Induced Obesity in Vivo Mouse Model

Por Fromont, Christophe, Atzori, Alessio, Kaur, Divneet, Hashmi, Lubna, Greco, Graziella, Cabanillas, Alejandro, Nguyen, Huy Van, Jones, D. Heulyn, Garzón, Miguel, Varela, Ana, Stevenson, Brett, Iacobini, Greg P., Lenoir, Marc, Rajesh, Sundaresan, Box, Clare, Kumar, Jitendra, Grant, Paige, Novitskaya, Vera, Morgan, Juliet, Sorrell, Fiona J., Redondo, Clara, Kramer, Andreas, Harris, C. John, Leighton, Brendan, Vickers, Steven P., Cheetham, Sharon C., Kenyon, Colin, Grabowska, Anna M., Overduin, Michael, Berditchevski, Fedor, Weston, Chris J., Knapp, Stefan, Fischer, Peter M., Butterworth, Sam
Publicado no J Med Chem (2020)