How close are we to implementing gene targeting in animals other than the mouse?

door Capecchi, Mario R.
Gepubliceerd in 2000

Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control development of the mammary gland in response to pregnancy

door Chen, Feng, Capecchi, Mario R.
Gepubliceerd in 1999

Bmi1 lineage tracing identifies a self-renewing pancreatic acinar cell subpopulation capable of maintaining pancreatic organ homeostasis

door Sangiorgi, Eugenio, Capecchi, Mario R.
Gepubliceerd in 2009

Bmi1 is expressed in vivo in intestinal stem cells

door Sangiorgi, Eugenio, Capecchi, Mario R
Gepubliceerd in 2008

Hoxa1 lineage-tracing indicates a direct role for Hoxa1 in development of the inner ear, the heart and the third rhombomere

door Makki, Nadja, Capecchi, Mario R.
Gepubliceerd in 2010

Identification of novel Hoxa1 downstream targets regulating hindbrain, neural crest and inner ear development

door Makki, Nadja, Capecchi, Mario R.
Gepubliceerd in 2011

Cardiovascular defects in a mouse model of HOXA1 syndrome

door Makki, Nadja, Capecchi, Mario R.
Gepubliceerd in 2012

Hoxc8 initiates an ectopic mammary program by regulating Fgf10 and Tbx3 expression and Wnt/β-catenin signaling

door Carroll, Lara S., Capecchi, Mario R.
Gepubliceerd in Development (2015)

ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination

door Capecchi, Mario R., Pozner, Amir
Gepubliceerd in Nat Commun (2015)

Hoxc13 mutant mice lack external hair

door Godwin, Alan R., Capecchi, Mario R.
Gepubliceerd in 1998

Fgf8 is required for outgrowth and patterning of the limbs

door Moon, Anne M., Capecchi, Mario R.
Gepubliceerd in 2000

Signaling by FGF4 and FGF8 is required for axial elongation of the mouse embryo

door Boulet, Anne M., Capecchi, Mario R.
Gepubliceerd in 2012

Lrig1 expression prospectively identifies stem cells in the ventricular-subventricular zone that are neurogenic throughout adult life

door Nam, Hyung-song, Capecchi, Mario R.
Gepubliceerd in Neural Dev (2020)

The housekeeping gene xanthine oxidoreductase is necessary for milk fat droplet enveloping and secretion: gene sharing in the lactating mammary gland

door Vorbach, Claudia, Scriven, Alistair, Capecchi, Mario R.
Gepubliceerd in 2002

In vivo evaluation of PhiC31 recombinase activity using a self-excision cassette

door Sangiorgi, Eugenio, Shuhua, Zhang, Capecchi, Mario R.
Gepubliceerd in 2008

Sequence-Independent Assembly of Spermatid mRNAs into Messenger Ribonucleoprotein Particles

door Schmidt, Edward E., Hanson, Eric S., Capecchi, Mario R.
Gepubliceerd in 1999

Synovial Sarcoma: From Genetics to Genetic-based Animal Modeling

door Haldar, Malay, Randall, R. Lor, Capecchi, Mario R.
Gepubliceerd in 2008

Hox11 paralogous genes are essential for metanephric kidney induction

door Wellik, Deneen M., Hawkes, Patrick J., Capecchi, Mario R.
Gepubliceerd in 2002

Normal limb development in conditional mutants of Fgf4

door Moon, Anne M., Boulet, Anne M., Capecchi, Mario R.
Gepubliceerd in 2000

Two Cell Lineages, myf5 and myf5-Independent, Participate in Mouse Skeletal Myogenesis

door Haldar, Malay, Karan, Goutam, Tvrdik, Petr, Capecchi, Mario R.
Gepubliceerd in 2008