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Fgf8 is required for outgrowth and patterning of the limbs

The expression pattern and activity of fibroblast growth factor-8 (FGF8) in experimental assays indicate that it has important roles in limb development 1-3, but early embryonic lethality resulting from mutation of Fgf8 in the germ line of mice has prevented direct assessment of these roles4. Here w...

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Detalhes bibliográficos
Main Authors: Moon, Anne M., Capecchi, Mario R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2001274/
https://ncbi.nlm.nih.gov/pubmed/11101845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/82601
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