Discovery of MK-1220: A Macrocyclic Inhibitor of Hepatitis C Virus NS3/4A Protease with Improved Preclinical Plasma Exposure

Por Rudd, Michael T., McCauley, John A., Butcher, John W., Romano, Joseph J., McIntyre, Charles J., Nguyen, Kevin T., Gilbert, Kevin F., Bush, Kimberly J., Holloway, M. Katharine, Swestock, John, Wan, Bang-Lin, Carroll, Steven S., DiMuzio, Jillian M., Graham, Donald J., Ludmerer, Steven W., Stahlhut, Mark W., Fandozzi, Christine M., Trainor, Nicole, Olsen, David B., Vacca, Joseph P., Liverton, Nigel J.
Publicado em 2011

Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor

Por Harper, Steven, McCauley, John A., Rudd, Michael T., Ferrara, Marco, DiFilippo, Marcello, Crescenzi, Benedetta, Koch, Uwe, Petrocchi, Alessia, Holloway, M. Katharine, Butcher, John W., Romano, Joseph J., Bush, Kimberly J., Gilbert, Kevin F., McIntyre, Charles J., Nguyen, Kevin T., Nizi, Emanuela, Carroll, Steven S., Ludmerer, Steven W., Burlein, Christine, DiMuzio, Jillian M., Graham, Donald J., McHale, Carolyn M., Stahlhut, Mark W., Olsen, David B., Monteagudo, Edith, Cianetti, Simona, Giuliano, Claudio, Pucci, Vincenzo, Trainor, Nicole, Fandozzi, Christine M., Rowley, Michael, Coleman, Paul J., Vacca, Joseph P., Summa, Vincenzo, Liverton, Nigel J.
Publicado em 2012