Adenoviral Delivery of Angiotensin-(1-7) or Angiotensin-(1-9) Inhibits Cardiomyocyte Hypertrophy via the Mas or Angiotensin Type 2 Receptor

di Flores-Muñoz, Monica, Godinho, Bruno M. D. C., Almalik, Abdulaziz, Nicklin, Stuart A.
Pubblicazione 2012

Utilization of modified surfactant-associated protein B for delivery of DNA to airway cells in culture.

di Baatz, J E, Bruno, M D, Ciraolo, P J, Glasser, S W, Stripp, B R, Smyth, K L, Korfhagen, T R
Pubblicazione 1994

Postnatal lung function and morphology in transgenic mice expressing transforming growth factor-alpha.

di Hardie, W. D., Bruno, M. D., Huelsman, K. M., Iwamoto, H. S., Carrigan, P. E., Leikauf, G. D., Whitsett, J. A., Korfhagen, T. R.
Pubblicazione 1997

Cis-acting sequences from a human surfactant protein gene confer pulmonary-specific gene expression in transgenic mice.

di Korfhagen, T R, Glasser, S W, Wert, S E, Bruno, M D, Daugherty, C C, McNeish, J D, Stock, J L, Potter, S S, Whitsett, J A
Pubblicazione 1990

A High-Throughput Method for Direct Detection of Therapeutic Oligonucleotide-Induced Gene Silencing In Vivo

di Coles, Andrew H., Osborn, Maire F., Alterman, Julia F., Turanov, Anton A., Godinho, Bruno M.D.C., Kennington, Lori, Chase, Kathryn, Aronin, Neil, Khvorova, Anastasia
Pubblicato in Nucleic Acid Ther (2016)

5΄-Vinylphosphonate improves tissue accumulation and efficacy of conjugated siRNAs in vivo

di Haraszti, Reka A., Roux, Loic, Coles, Andrew H., Turanov, Anton A., Alterman, Julia F., Echeverria, Dimas, Godinho, Bruno M.D.C., Aronin, Neil, Khvorova, Anastasia
Pubblicato in Nucleic Acids Res (2017)

Pharmacokinetic Profiling of Conjugated Therapeutic Oligonucleotides: A High-Throughput Method Based Upon Serial Blood Microsampling Coupled to Peptide Nucleic Acid Hybridization A...

di Godinho, Bruno M.D.C., Gilbert, James W., Haraszti, Reka A., Coles, Andrew H., Biscans, Annabelle, Roux, Loic, Nikan, Mehran, Echeverria, Dimas, Hassler, Matthew, Khvorova, Anastasia
Pubblicato in Nucleic Acid Ther (2017)

Synthesis and Evaluation of Parenchymal Retention and Efficacy of a Metabolically Stable, O-phosphocholine-N-docosahexaenoyl-L-serine siRNA Conjugate in Mouse Brain

di Nikan, Mehran, Osborn, Maire F., Coles, Andrew H., Biscans, Annabelle, Godinho, Bruno M.D.C., Haraszti, Reka A., Sapp, Ellen, Echeverria, Dimas, DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia
Pubblicato in Bioconjug Chem (2017)

Hydrophobicity drives the systemic distribution of lipid-conjugated siRNAs via lipid transport pathways

di Osborn, Maire F, Coles, Andrew H, Biscans, Annabelle, Haraszti, Reka A, Roux, Loic, Davis, Sarah, Ly, Socheata, Echeverria, Dimas, Hassler, Matthew R, Godinho, Bruno M D C, Nikan, Mehran, Khvorova, Anastasia
Pubblicato in Nucleic Acids Res (2019)

Altered surfactant function and structure in SP-A gene targeted mice.

di Korfhagen, T R, Bruno, M D, Ross, G F, Huelsman, K M, Ikegami, M, Jobe, A H, Wert, S E, Stripp, B R, Morris, R E, Glasser, S W, Bachurski, C J, Iwamoto, H S, Whitsett, J A
Pubblicazione 1996

Transvascular Delivery of Hydrophobically Modified siRNAs: Gene Silencing in the Rat Brain upon Disruption of the Blood-Brain Barrier

di Godinho, Bruno M.D.C., Henninger, Nils, Bouley, James, Alterman, Julia F., Haraszti, Reka A., Gilbert, James W., Sapp, Ellen, Coles, Andrew H., Biscans, Annabelle, Nikan, Mehran, Echeverria, Dimas, DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia
Pubblicato in Mol Ther (2018)

Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo

di Hassler, Matthew R, Turanov, Anton A, Alterman, Julia F, Haraszti, Reka A, Coles, Andrew H, Osborn, Maire F, Echeverria, Dimas, Nikan, Mehran, Salomon, William E, Roux, Loïc, Godinho, Bruno M D C, Davis, Sarah M, Morrissey, David V, Zamore, Phillip D, Karumanchi, S Ananth, Moore, Melissa J, Aronin, Neil, Khvorova, Anastasia
Pubblicato in Nucleic Acids Res (2018)

Serum Deprivation of Mesenchymal Stem Cells Improves Exosome Activity and Alters Lipid and Protein Composition

di Haraszti, Reka Agnes, Miller, Rachael, Dubuke, Michelle L., Rockwell, Hannah E., Coles, Andrew H., Sapp, Ellen, Didiot, Marie-Cecile, Echeverria, Dimas, Stoppato, Matteo, Sere, Yves Y., Leszyk, John, Alterman, Julia F., Godinho, Bruno M.D.C., Hassler, Matthew R., McDaniel, Justice, Narain, Niven R., Wollacott, Rachel, Wang, Yang, Shaffer, Scott A., Kiebish, Michael A., DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia
Pubblicato in iScience (2019)

A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system

di Alterman, Julia F., Godinho, Bruno M.D.C., Hassler, Matthew R., Ferguson, Chantal M., Echeverria, Dimas, Sapp, Ellen, Haraszti, Reka A., Coles, Andrew H., Conroy, Faith, Miller, Rachael, Roux, Loic, Yan, Paul, Knox, Emily G., Turanov, Anton A., King, Robert M., Gernoux, Gwladys, Mueller, Christian, Gray-Edwards, Heather L., Moser, Richard P., Bishop, Nina C., Jaber, Samer M., Gounis, Matthew J., Sena-Esteves, Miguel, Pai, Athma A., DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia
Pubblicato in Nat Biotechnol (2019)