Resolving self-association of a therapeutic antibody by formulation optimization and molecular approaches

por Casaz, Paul, Boucher, Elisabeth, Wollacott, Rachel, Pierce, Brian G, Rivera, Rachel, Sedic, Maja, Ozturk, Sadettin, Thomas, William D, Wang, Yang
Publicado no MAbs (2014)

Analytical characterization of a monoclonal antibody therapeutic reveals a three-light chain species that is efficiently removed using hydrophobic interaction chromatography

por Wollacott, Rachel B, Casaz, Paul L, Morin, Trevor J, Zhu, H Lily, Anderson, Roger S, Babcock, Gregory J, Que, John, Thomas Jr, William D, Ozturk, Sadettin S
Publicado em 2013

Exosomes Produced from 3D Cultures of MSCs by Tangential Flow Filtration Show Higher Yield and Improved Activity

por Haraszti, Reka Agnes, Miller, Rachael, Stoppato, Matteo, Sere, Yves Y., Coles, Andrew, Didiot, Marie-Cecile, Wollacott, Rachel, Sapp, Ellen, Dubuke, Michelle L., Li, Xuni, Shaffer, Scott A., DiFiglia, Marian, Wang, Yang, Aronin, Neil, Khvorova, Anastasia
Publicado no Mol Ther (2018)

Serum Deprivation of Mesenchymal Stem Cells Improves Exosome Activity and Alters Lipid and Protein Composition

por Haraszti, Reka Agnes, Miller, Rachael, Dubuke, Michelle L., Rockwell, Hannah E., Coles, Andrew H., Sapp, Ellen, Didiot, Marie-Cecile, Echeverria, Dimas, Stoppato, Matteo, Sere, Yves Y., Leszyk, John, Alterman, Julia F., Godinho, Bruno M.D.C., Hassler, Matthew R., McDaniel, Justice, Narain, Niven R., Wollacott, Rachel, Wang, Yang, Shaffer, Scott A., Kiebish, Michael A., DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia
Publicado no iScience (2019)