Adenoviral Delivery of Angiotensin-(1-7) or Angiotensin-(1-9) Inhibits Cardiomyocyte Hypertrophy via the Mas or Angiotensin Type 2 Receptor

מאת Flores-Muñoz, Monica, Godinho, Bruno M. D. C., Almalik, Abdulaziz, Nicklin, Stuart A.
יצא לאור 2012

Utilization of modified surfactant-associated protein B for delivery of DNA to airway cells in culture.

מאת Baatz, J E, Bruno, M D, Ciraolo, P J, Glasser, S W, Stripp, B R, Smyth, K L, Korfhagen, T R
יצא לאור 1994

Postnatal lung function and morphology in transgenic mice expressing transforming growth factor-alpha.

מאת Hardie, W. D., Bruno, M. D., Huelsman, K. M., Iwamoto, H. S., Carrigan, P. E., Leikauf, G. D., Whitsett, J. A., Korfhagen, T. R.
יצא לאור 1997

Cis-acting sequences from a human surfactant protein gene confer pulmonary-specific gene expression in transgenic mice.

מאת Korfhagen, T R, Glasser, S W, Wert, S E, Bruno, M D, Daugherty, C C, McNeish, J D, Stock, J L, Potter, S S, Whitsett, J A
יצא לאור 1990

A High-Throughput Method for Direct Detection of Therapeutic Oligonucleotide-Induced Gene Silencing In Vivo

מאת Coles, Andrew H., Osborn, Maire F., Alterman, Julia F., Turanov, Anton A., Godinho, Bruno M.D.C., Kennington, Lori, Chase, Kathryn, Aronin, Neil, Khvorova, Anastasia
הוצא לאור ב Nucleic Acid Ther (2016)

5΄-Vinylphosphonate improves tissue accumulation and efficacy of conjugated siRNAs in vivo

מאת Haraszti, Reka A., Roux, Loic, Coles, Andrew H., Turanov, Anton A., Alterman, Julia F., Echeverria, Dimas, Godinho, Bruno M.D.C., Aronin, Neil, Khvorova, Anastasia
הוצא לאור ב Nucleic Acids Res (2017)

Pharmacokinetic Profiling of Conjugated Therapeutic Oligonucleotides: A High-Throughput Method Based Upon Serial Blood Microsampling Coupled to Peptide Nucleic Acid Hybridization A...

מאת Godinho, Bruno M.D.C., Gilbert, James W., Haraszti, Reka A., Coles, Andrew H., Biscans, Annabelle, Roux, Loic, Nikan, Mehran, Echeverria, Dimas, Hassler, Matthew, Khvorova, Anastasia
הוצא לאור ב Nucleic Acid Ther (2017)

Synthesis and Evaluation of Parenchymal Retention and Efficacy of a Metabolically Stable, O-phosphocholine-N-docosahexaenoyl-L-serine siRNA Conjugate in Mouse Brain

מאת Nikan, Mehran, Osborn, Maire F., Coles, Andrew H., Biscans, Annabelle, Godinho, Bruno M.D.C., Haraszti, Reka A., Sapp, Ellen, Echeverria, Dimas, DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia
הוצא לאור ב Bioconjug Chem (2017)

Hydrophobicity drives the systemic distribution of lipid-conjugated siRNAs via lipid transport pathways

מאת Osborn, Maire F, Coles, Andrew H, Biscans, Annabelle, Haraszti, Reka A, Roux, Loic, Davis, Sarah, Ly, Socheata, Echeverria, Dimas, Hassler, Matthew R, Godinho, Bruno M D C, Nikan, Mehran, Khvorova, Anastasia
הוצא לאור ב Nucleic Acids Res (2019)

Altered surfactant function and structure in SP-A gene targeted mice.

מאת Korfhagen, T R, Bruno, M D, Ross, G F, Huelsman, K M, Ikegami, M, Jobe, A H, Wert, S E, Stripp, B R, Morris, R E, Glasser, S W, Bachurski, C J, Iwamoto, H S, Whitsett, J A
יצא לאור 1996

Transvascular Delivery of Hydrophobically Modified siRNAs: Gene Silencing in the Rat Brain upon Disruption of the Blood-Brain Barrier

מאת Godinho, Bruno M.D.C., Henninger, Nils, Bouley, James, Alterman, Julia F., Haraszti, Reka A., Gilbert, James W., Sapp, Ellen, Coles, Andrew H., Biscans, Annabelle, Nikan, Mehran, Echeverria, Dimas, DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia
הוצא לאור ב Mol Ther (2018)

Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo

מאת Hassler, Matthew R, Turanov, Anton A, Alterman, Julia F, Haraszti, Reka A, Coles, Andrew H, Osborn, Maire F, Echeverria, Dimas, Nikan, Mehran, Salomon, William E, Roux, Loïc, Godinho, Bruno M D C, Davis, Sarah M, Morrissey, David V, Zamore, Phillip D, Karumanchi, S Ananth, Moore, Melissa J, Aronin, Neil, Khvorova, Anastasia
הוצא לאור ב Nucleic Acids Res (2018)

Serum Deprivation of Mesenchymal Stem Cells Improves Exosome Activity and Alters Lipid and Protein Composition

מאת Haraszti, Reka Agnes, Miller, Rachael, Dubuke, Michelle L., Rockwell, Hannah E., Coles, Andrew H., Sapp, Ellen, Didiot, Marie-Cecile, Echeverria, Dimas, Stoppato, Matteo, Sere, Yves Y., Leszyk, John, Alterman, Julia F., Godinho, Bruno M.D.C., Hassler, Matthew R., McDaniel, Justice, Narain, Niven R., Wollacott, Rachel, Wang, Yang, Shaffer, Scott A., Kiebish, Michael A., DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia
הוצא לאור ב iScience (2019)

A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system

מאת Alterman, Julia F., Godinho, Bruno M.D.C., Hassler, Matthew R., Ferguson, Chantal M., Echeverria, Dimas, Sapp, Ellen, Haraszti, Reka A., Coles, Andrew H., Conroy, Faith, Miller, Rachael, Roux, Loic, Yan, Paul, Knox, Emily G., Turanov, Anton A., King, Robert M., Gernoux, Gwladys, Mueller, Christian, Gray-Edwards, Heather L., Moser, Richard P., Bishop, Nina C., Jaber, Samer M., Gounis, Matthew J., Sena-Esteves, Miguel, Pai, Athma A., DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia
הוצא לאור ב Nat Biotechnol (2019)