Adenoviral Delivery of Angiotensin-(1-7) or Angiotensin-(1-9) Inhibits Cardiomyocyte Hypertrophy via the Mas or Angiotensin Type 2 Receptor

gan Flores-Muñoz, Monica, Godinho, Bruno M. D. C., Almalik, Abdulaziz, Nicklin, Stuart A.
Cyhoeddwyd 2012

Utilization of modified surfactant-associated protein B for delivery of DNA to airway cells in culture.

gan Baatz, J E, Bruno, M D, Ciraolo, P J, Glasser, S W, Stripp, B R, Smyth, K L, Korfhagen, T R
Cyhoeddwyd 1994

Postnatal lung function and morphology in transgenic mice expressing transforming growth factor-alpha.

gan Hardie, W. D., Bruno, M. D., Huelsman, K. M., Iwamoto, H. S., Carrigan, P. E., Leikauf, G. D., Whitsett, J. A., Korfhagen, T. R.
Cyhoeddwyd 1997

Cis-acting sequences from a human surfactant protein gene confer pulmonary-specific gene expression in transgenic mice.

gan Korfhagen, T R, Glasser, S W, Wert, S E, Bruno, M D, Daugherty, C C, McNeish, J D, Stock, J L, Potter, S S, Whitsett, J A
Cyhoeddwyd 1990

A High-Throughput Method for Direct Detection of Therapeutic Oligonucleotide-Induced Gene Silencing In Vivo

gan Coles, Andrew H., Osborn, Maire F., Alterman, Julia F., Turanov, Anton A., Godinho, Bruno M.D.C., Kennington, Lori, Chase, Kathryn, Aronin, Neil, Khvorova, Anastasia
Cyhoeddwyd yn Nucleic Acid Ther (2016)

5΄-Vinylphosphonate improves tissue accumulation and efficacy of conjugated siRNAs in vivo

gan Haraszti, Reka A., Roux, Loic, Coles, Andrew H., Turanov, Anton A., Alterman, Julia F., Echeverria, Dimas, Godinho, Bruno M.D.C., Aronin, Neil, Khvorova, Anastasia
Cyhoeddwyd yn Nucleic Acids Res (2017)

Pharmacokinetic Profiling of Conjugated Therapeutic Oligonucleotides: A High-Throughput Method Based Upon Serial Blood Microsampling Coupled to Peptide Nucleic Acid Hybridization A...

gan Godinho, Bruno M.D.C., Gilbert, James W., Haraszti, Reka A., Coles, Andrew H., Biscans, Annabelle, Roux, Loic, Nikan, Mehran, Echeverria, Dimas, Hassler, Matthew, Khvorova, Anastasia
Cyhoeddwyd yn Nucleic Acid Ther (2017)

Synthesis and Evaluation of Parenchymal Retention and Efficacy of a Metabolically Stable, O-phosphocholine-N-docosahexaenoyl-L-serine siRNA Conjugate in Mouse Brain

gan Nikan, Mehran, Osborn, Maire F., Coles, Andrew H., Biscans, Annabelle, Godinho, Bruno M.D.C., Haraszti, Reka A., Sapp, Ellen, Echeverria, Dimas, DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia
Cyhoeddwyd yn Bioconjug Chem (2017)

Hydrophobicity drives the systemic distribution of lipid-conjugated siRNAs via lipid transport pathways

gan Osborn, Maire F, Coles, Andrew H, Biscans, Annabelle, Haraszti, Reka A, Roux, Loic, Davis, Sarah, Ly, Socheata, Echeverria, Dimas, Hassler, Matthew R, Godinho, Bruno M D C, Nikan, Mehran, Khvorova, Anastasia
Cyhoeddwyd yn Nucleic Acids Res (2019)

Altered surfactant function and structure in SP-A gene targeted mice.

gan Korfhagen, T R, Bruno, M D, Ross, G F, Huelsman, K M, Ikegami, M, Jobe, A H, Wert, S E, Stripp, B R, Morris, R E, Glasser, S W, Bachurski, C J, Iwamoto, H S, Whitsett, J A
Cyhoeddwyd 1996

Transvascular Delivery of Hydrophobically Modified siRNAs: Gene Silencing in the Rat Brain upon Disruption of the Blood-Brain Barrier

gan Godinho, Bruno M.D.C., Henninger, Nils, Bouley, James, Alterman, Julia F., Haraszti, Reka A., Gilbert, James W., Sapp, Ellen, Coles, Andrew H., Biscans, Annabelle, Nikan, Mehran, Echeverria, Dimas, DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia
Cyhoeddwyd yn Mol Ther (2018)

Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo

gan Hassler, Matthew R, Turanov, Anton A, Alterman, Julia F, Haraszti, Reka A, Coles, Andrew H, Osborn, Maire F, Echeverria, Dimas, Nikan, Mehran, Salomon, William E, Roux, Loïc, Godinho, Bruno M D C, Davis, Sarah M, Morrissey, David V, Zamore, Phillip D, Karumanchi, S Ananth, Moore, Melissa J, Aronin, Neil, Khvorova, Anastasia
Cyhoeddwyd yn Nucleic Acids Res (2018)

Serum Deprivation of Mesenchymal Stem Cells Improves Exosome Activity and Alters Lipid and Protein Composition

gan Haraszti, Reka Agnes, Miller, Rachael, Dubuke, Michelle L., Rockwell, Hannah E., Coles, Andrew H., Sapp, Ellen, Didiot, Marie-Cecile, Echeverria, Dimas, Stoppato, Matteo, Sere, Yves Y., Leszyk, John, Alterman, Julia F., Godinho, Bruno M.D.C., Hassler, Matthew R., McDaniel, Justice, Narain, Niven R., Wollacott, Rachel, Wang, Yang, Shaffer, Scott A., Kiebish, Michael A., DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia
Cyhoeddwyd yn iScience (2019)

A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system

gan Alterman, Julia F., Godinho, Bruno M.D.C., Hassler, Matthew R., Ferguson, Chantal M., Echeverria, Dimas, Sapp, Ellen, Haraszti, Reka A., Coles, Andrew H., Conroy, Faith, Miller, Rachael, Roux, Loic, Yan, Paul, Knox, Emily G., Turanov, Anton A., King, Robert M., Gernoux, Gwladys, Mueller, Christian, Gray-Edwards, Heather L., Moser, Richard P., Bishop, Nina C., Jaber, Samer M., Gounis, Matthew J., Sena-Esteves, Miguel, Pai, Athma A., DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia
Cyhoeddwyd yn Nat Biotechnol (2019)