Adenoviral Delivery of Angiotensin-(1-7) or Angiotensin-(1-9) Inhibits Cardiomyocyte Hypertrophy via the Mas or Angiotensin Type 2 Receptor

per Flores-Muñoz, Monica, Godinho, Bruno M. D. C., Almalik, Abdulaziz, Nicklin, Stuart A.
Publicat 2012

Utilization of modified surfactant-associated protein B for delivery of DNA to airway cells in culture.

per Baatz, J E, Bruno, M D, Ciraolo, P J, Glasser, S W, Stripp, B R, Smyth, K L, Korfhagen, T R
Publicat 1994

Postnatal lung function and morphology in transgenic mice expressing transforming growth factor-alpha.

per Hardie, W. D., Bruno, M. D., Huelsman, K. M., Iwamoto, H. S., Carrigan, P. E., Leikauf, G. D., Whitsett, J. A., Korfhagen, T. R.
Publicat 1997

Cis-acting sequences from a human surfactant protein gene confer pulmonary-specific gene expression in transgenic mice.

per Korfhagen, T R, Glasser, S W, Wert, S E, Bruno, M D, Daugherty, C C, McNeish, J D, Stock, J L, Potter, S S, Whitsett, J A
Publicat 1990

A High-Throughput Method for Direct Detection of Therapeutic Oligonucleotide-Induced Gene Silencing In Vivo

per Coles, Andrew H., Osborn, Maire F., Alterman, Julia F., Turanov, Anton A., Godinho, Bruno M.D.C., Kennington, Lori, Chase, Kathryn, Aronin, Neil, Khvorova, Anastasia
Publicat a Nucleic Acid Ther (2016)

5΄-Vinylphosphonate improves tissue accumulation and efficacy of conjugated siRNAs in vivo

per Haraszti, Reka A., Roux, Loic, Coles, Andrew H., Turanov, Anton A., Alterman, Julia F., Echeverria, Dimas, Godinho, Bruno M.D.C., Aronin, Neil, Khvorova, Anastasia
Publicat a Nucleic Acids Res (2017)

Pharmacokinetic Profiling of Conjugated Therapeutic Oligonucleotides: A High-Throughput Method Based Upon Serial Blood Microsampling Coupled to Peptide Nucleic Acid Hybridization A...

per Godinho, Bruno M.D.C., Gilbert, James W., Haraszti, Reka A., Coles, Andrew H., Biscans, Annabelle, Roux, Loic, Nikan, Mehran, Echeverria, Dimas, Hassler, Matthew, Khvorova, Anastasia
Publicat a Nucleic Acid Ther (2017)

Synthesis and Evaluation of Parenchymal Retention and Efficacy of a Metabolically Stable, O-phosphocholine-N-docosahexaenoyl-L-serine siRNA Conjugate in Mouse Brain

per Nikan, Mehran, Osborn, Maire F., Coles, Andrew H., Biscans, Annabelle, Godinho, Bruno M.D.C., Haraszti, Reka A., Sapp, Ellen, Echeverria, Dimas, DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia
Publicat a Bioconjug Chem (2017)

Hydrophobicity drives the systemic distribution of lipid-conjugated siRNAs via lipid transport pathways

per Osborn, Maire F, Coles, Andrew H, Biscans, Annabelle, Haraszti, Reka A, Roux, Loic, Davis, Sarah, Ly, Socheata, Echeverria, Dimas, Hassler, Matthew R, Godinho, Bruno M D C, Nikan, Mehran, Khvorova, Anastasia
Publicat a Nucleic Acids Res (2019)

Altered surfactant function and structure in SP-A gene targeted mice.

per Korfhagen, T R, Bruno, M D, Ross, G F, Huelsman, K M, Ikegami, M, Jobe, A H, Wert, S E, Stripp, B R, Morris, R E, Glasser, S W, Bachurski, C J, Iwamoto, H S, Whitsett, J A
Publicat 1996

Transvascular Delivery of Hydrophobically Modified siRNAs: Gene Silencing in the Rat Brain upon Disruption of the Blood-Brain Barrier

per Godinho, Bruno M.D.C., Henninger, Nils, Bouley, James, Alterman, Julia F., Haraszti, Reka A., Gilbert, James W., Sapp, Ellen, Coles, Andrew H., Biscans, Annabelle, Nikan, Mehran, Echeverria, Dimas, DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia
Publicat a Mol Ther (2018)

Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo

per Hassler, Matthew R, Turanov, Anton A, Alterman, Julia F, Haraszti, Reka A, Coles, Andrew H, Osborn, Maire F, Echeverria, Dimas, Nikan, Mehran, Salomon, William E, Roux, Loïc, Godinho, Bruno M D C, Davis, Sarah M, Morrissey, David V, Zamore, Phillip D, Karumanchi, S Ananth, Moore, Melissa J, Aronin, Neil, Khvorova, Anastasia
Publicat a Nucleic Acids Res (2018)

Serum Deprivation of Mesenchymal Stem Cells Improves Exosome Activity and Alters Lipid and Protein Composition

per Haraszti, Reka Agnes, Miller, Rachael, Dubuke, Michelle L., Rockwell, Hannah E., Coles, Andrew H., Sapp, Ellen, Didiot, Marie-Cecile, Echeverria, Dimas, Stoppato, Matteo, Sere, Yves Y., Leszyk, John, Alterman, Julia F., Godinho, Bruno M.D.C., Hassler, Matthew R., McDaniel, Justice, Narain, Niven R., Wollacott, Rachel, Wang, Yang, Shaffer, Scott A., Kiebish, Michael A., DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia
Publicat a iScience (2019)

A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system

per Alterman, Julia F., Godinho, Bruno M.D.C., Hassler, Matthew R., Ferguson, Chantal M., Echeverria, Dimas, Sapp, Ellen, Haraszti, Reka A., Coles, Andrew H., Conroy, Faith, Miller, Rachael, Roux, Loic, Yan, Paul, Knox, Emily G., Turanov, Anton A., King, Robert M., Gernoux, Gwladys, Mueller, Christian, Gray-Edwards, Heather L., Moser, Richard P., Bishop, Nina C., Jaber, Samer M., Gounis, Matthew J., Sena-Esteves, Miguel, Pai, Athma A., DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia
Publicat a Nat Biotechnol (2019)