Unexpected mechanisms of action for a cytokine receptor-blocking antibody

par Hercus, Timothy R, Broughton, Sophie E, Hardy, Matthew P, Nero, Tracy L, Wilson, Nicholas J, Parker, Michael W, Lopez, Angel F
Publié dans Mol Cell Oncol (2014)

The production and crystallization of the human leukocyte antigen class II molecules HLA-DQ2 and HLA-DQ8 complexed with deamidated gliadin peptides implicated in coeliac disease

par Henderson, Kate N., Reid, Hugh H., Borg, Natalie A., Broughton, Sophie E., Huyton, Trevor, Anderson, Robert P., McCluskey, James, Rossjohn, Jamie
Publié 2007

EPO does not promote interaction between the erythropoietin and beta-common receptors

par Cheung Tung Shing, Karen S., Broughton, Sophie E., Nero, Tracy L., Gillinder, Kevin, Ilsley, Melissa D., Ramshaw, Hayley, Lopez, Angel F., Griffin, Michael D. W., Parker, Michael W., Perkins, Andrew C., Dhagat, Urmi
Publié dans Sci Rep (2018)

Author Correction: EPO does not promote interaction between the erythropoietin and beta-common receptors

par Cheung Tung Shing, Karen S., Broughton, Sophie E., Nero, Tracy L., Gillinder, Kevin, Ilsley, Melissa D., Ramshaw, Hayley, Lopez, Angel F., Griffin, Michael D. W., Parker, Michael W., Perkins, Andrew C., Dhagat, Urmi
Publié dans Sci Rep (2019)

Crystallization and preliminary X-ray diffraction analysis of the interleukin-3 alpha receptor bound to the Fab fragment of antibody CSL362

par Broughton, Sophie E., Hercus, Timothy R., Nero, Tracy L., Dhagat, Urmi, Owczarek, Catherine M., Hardy, Matthew P., Fabri, Louis J., Scotney, Pierre D., Nash, Andrew D., Wilson, Nicholas J., Lopez, Angel F., Parker, Michael W.
Publié 2014

The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities

par Dhagat, Urmi, Hercus, Timothy R., Broughton, Sophie E., Nero, Tracy L., Cheung Tung Shing, Karen S., Barry, Emma F., Thomson, Christy A., Bryson, Steve, Pai, Emil F., McClure, Barbara J., Schrader, John W., Lopez, Angel F., Parker, Michael W.
Publié dans MAbs (2018)

A dual role for the N-terminal domain of the IL-3 receptor in cell signalling

par Broughton, Sophie E., Hercus, Timothy R., Nero, Tracy L., Kan, Winnie L., Barry, Emma F., Dottore, Mara, Cheung Tung Shing, Karen S., Morton, Craig J., Dhagat, Urmi, Hardy, Matthew P., Wilson, Nicholas J., Downton, Matthew T., Schieber, Christine, Hughes, Timothy P., Lopez, Angel F., Parker, Michael W.
Publié dans Nat Commun (2018)

Role of the β Common (βc) Family of Cytokines in Health and Disease

par Hercus, Timothy R., Kan, Winnie L. T., Broughton, Sophie E., Tvorogov, Denis, Ramshaw, Hayley S., Sandow, Jarrod J., Nero, Tracy L., Dhagat, Urmi, Thompson, Emma J., Shing, Karen S. Cheung Tung, McKenzie, Duncan R., Wilson, Nicholas J., Owczarek, Catherine M., Vairo, Gino, Nash, Andrew D., Tergaonkar, Vinay, Hughes, Timothy, Ekert, Paul G., Samuel, Michael S., Bonder, Claudine S., Grimbaldeston, Michele A., Parker, Michael W., Lopez, Angel F.
Publié dans Cold Spring Harb Perspect Biol (2018)