Unexpected mechanisms of action for a cytokine receptor-blocking antibody

by Hercus, Timothy R, Broughton, Sophie E, Hardy, Matthew P, Nero, Tracy L, Wilson, Nicholas J, Parker, Michael W, Lopez, Angel F
Published in Mol Cell Oncol (2014)

The production and crystallization of the human leukocyte antigen class II molecules HLA-DQ2 and HLA-DQ8 complexed with deamidated gliadin peptides implicated in coeliac disease

by Henderson, Kate N., Reid, Hugh H., Borg, Natalie A., Broughton, Sophie E., Huyton, Trevor, Anderson, Robert P., McCluskey, James, Rossjohn, Jamie
Published 2007

EPO does not promote interaction between the erythropoietin and beta-common receptors

by Cheung Tung Shing, Karen S., Broughton, Sophie E., Nero, Tracy L., Gillinder, Kevin, Ilsley, Melissa D., Ramshaw, Hayley, Lopez, Angel F., Griffin, Michael D. W., Parker, Michael W., Perkins, Andrew C., Dhagat, Urmi
Published in Sci Rep (2018)

Author Correction: EPO does not promote interaction between the erythropoietin and beta-common receptors

by Cheung Tung Shing, Karen S., Broughton, Sophie E., Nero, Tracy L., Gillinder, Kevin, Ilsley, Melissa D., Ramshaw, Hayley, Lopez, Angel F., Griffin, Michael D. W., Parker, Michael W., Perkins, Andrew C., Dhagat, Urmi
Published in Sci Rep (2019)

Crystallization and preliminary X-ray diffraction analysis of the interleukin-3 alpha receptor bound to the Fab fragment of antibody CSL362

by Broughton, Sophie E., Hercus, Timothy R., Nero, Tracy L., Dhagat, Urmi, Owczarek, Catherine M., Hardy, Matthew P., Fabri, Louis J., Scotney, Pierre D., Nash, Andrew D., Wilson, Nicholas J., Lopez, Angel F., Parker, Michael W.
Published 2014

The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities

by Dhagat, Urmi, Hercus, Timothy R., Broughton, Sophie E., Nero, Tracy L., Cheung Tung Shing, Karen S., Barry, Emma F., Thomson, Christy A., Bryson, Steve, Pai, Emil F., McClure, Barbara J., Schrader, John W., Lopez, Angel F., Parker, Michael W.
Published in MAbs (2018)

A dual role for the N-terminal domain of the IL-3 receptor in cell signalling

by Broughton, Sophie E., Hercus, Timothy R., Nero, Tracy L., Kan, Winnie L., Barry, Emma F., Dottore, Mara, Cheung Tung Shing, Karen S., Morton, Craig J., Dhagat, Urmi, Hardy, Matthew P., Wilson, Nicholas J., Downton, Matthew T., Schieber, Christine, Hughes, Timothy P., Lopez, Angel F., Parker, Michael W.
Published in Nat Commun (2018)

Role of the β Common (βc) Family of Cytokines in Health and Disease

by Hercus, Timothy R., Kan, Winnie L. T., Broughton, Sophie E., Tvorogov, Denis, Ramshaw, Hayley S., Sandow, Jarrod J., Nero, Tracy L., Dhagat, Urmi, Thompson, Emma J., Shing, Karen S. Cheung Tung, McKenzie, Duncan R., Wilson, Nicholas J., Owczarek, Catherine M., Vairo, Gino, Nash, Andrew D., Tergaonkar, Vinay, Hughes, Timothy, Ekert, Paul G., Samuel, Michael S., Bonder, Claudine S., Grimbaldeston, Michele A., Parker, Michael W., Lopez, Angel F.
Published in Cold Spring Harb Perspect Biol (2018)