Maternal Embryonic Leucine Zipper Kinase (MELK) Reduces Replication Stress in Glioblastoma Cells

Por Kig, Cenk, Beullens, Monique, Beke, Lijs, Van Eynde, Aleyde, Linders, Johannes T., Brehmer, Dirk, Bollen, Mathieu
Publicado em 2013

Binding specificity of Escherichia coli trigger factor

Por Patzelt, Holger, Rüdiger, Stefan, Brehmer, Dirk, Kramer, Günter, Vorderwülbecke, Sonja, Schaffitzel, Elke, Waitz, Andreas, Hesterkamp, Thomas, Dong, Liying, Schneider-Mergener, Jens, Bukau, Bernd, Deuerling, Elke
Publicado em 2001

Quantitative Phosphoproteomics Analysis of ERBB3/ERBB4 Signaling

Por Wandinger, Sebastian K., Lahortiga, Idoya, Jacobs, Kris, Klammer, Martin, Jordan, Nicole, Elschenbroich, Sarah, Parade, Marc, Jacoby, Edgar, Linders, Joannes T. M., Brehmer, Dirk, Cools, Jan, Daub, Henrik
Publicado no PLoS One (2016)

MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells

Por Beke, Lijs, Kig, Cenk, Linders, Joannes T. M., Boens, Shannah, Boeckx, An, van Heerde, Erika, Parade, Marc, De Bondt, An, Van den Wyngaert, Ilse, Bashir, Tarig, Ogata, Souichi, Meerpoel, Lieven, Van Eynde, Aleyde, Johnson, Christopher N., Beullens, Monique, Brehmer, Dirk, Bollen, Mathieu
Publicado no Biosci Rep (2015)

Fragment-Based Discovery of Type I Inhibitors of Maternal Embryonic Leucine Zipper Kinase

Por Johnson, Christopher N., Berdini, Valerio, Beke, Lijs, Bonnet, Pascal, Brehmer, Dirk, Coyle, Joseph E., Day, Phillip J., Frederickson, Martyn, Freyne, Eddy J. E., Gilissen, Ron A. H. J., Hamlett, Christopher C. F., Howard, Steven, Meerpoel, Lieven, McMenamin, Rachel, Patel, Sahil, Rees, David C., Sharff, Andrew, Sommen, François, Wu, Tongfei, Linders, Joannes T. M.
Publicado no ACS Med Chem Lett (2014)

Structure-Based Design of Type II Inhibitors Applied to Maternal Embryonic Leucine Zipper Kinase

Por Johnson, Christopher N., Adelinet, Christophe, Berdini, Valerio, Beke, Lijs, Bonnet, Pascal, Brehmer, Dirk, Calo, Frederick, Coyle, Joseph E., Day, Phillip J., Frederickson, Martyn, Freyne, Eddy J. E., Gilissen, Ron A. H. J., Hamlett, Christopher C. F., Howard, Steven, Meerpoel, Lieven, Mevellec, Laurence, McMenamin, Rachel, Pasquier, Elisabeth, Patel, Sahil, Rees, David C., Linders, Joannes T. M.
Publicado no ACS Med Chem Lett (2014)