An APC:WNT Counter-Current-Like Mechanism Regulates Cell Division Along the Human Colonic Crypt Axis: A Mechanism That Explains How APC Mutations Induce Proliferative Abnormalities...

por Boman, Bruce M., Fields, Jeremy Z.
Publicado 2013

Role of HOX Genes in Stem Cell Differentiation and Cancer

por Bhatlekar, Seema, Fields, Jeremy Z., Boman, Bruce M.
Publicado en Stem Cells Int (2018)

The Proportion of ALDEFLUOR-Positive Cancer Stem Cells Changes with Cell Culture Density Due to the Expression of Different ALDH Isoforms

por Opdenaker, Lynn M., Modarai, Shirin R., Boman, Bruce M.
Publicado en Cancer Stud Mol Med (2015)

Autocatalytic Tissue Polymerization Reaction Mechanism in Colorectal Cancer Development and Growth

por Boman, Bruce M., Guetter, Arthur, Boman, Ryan M., Runquist, Olaf A.
Publicado en Cancers (Basel) (2020)

The Role of miRNAs, miRNA Clusters, and isomiRs in Development of Cancer Stem Cell Populations in Colorectal Cancer

por Stark, Victoria A., Facey, Caroline O. B., Viswanathan, Vignesh, Boman, Bruce M.
Publicado en Int J Mol Sci (2021)

Retinoids as Chemo-Preventive and Molecular-Targeted Anti-Cancer Therapies

por Hunsu, Victoria O., Facey, Caroline O. B., Fields, Jeremy Z., Boman, Bruce M.
Publicado en Int J Mol Sci (2021)

Somatostatin signaling via SSTR1 contributes to the quiescence of colon cancer stem cells

por Modarai, Shirin R., Opdenaker, Lynn M., Viswanathan, Vignesh, Fields, Jeremy Z., Boman, Bruce M.
Publicado en BMC Cancer (2016)

MicroRNA Expression Profiling of Normal and Malignant Human Colonic Stem Cells Identifies miRNA92a as a Regulator of the LRIG1 Stem Cell Gene

por Viswanathan, Vignesh, Opdenaker, Lynn, Modarai, Shirin, Fields, Jeremy Z., Gonye, Gregory, Boman, Bruce M.
Publicado en Int J Mol Sci (2020)

Increased Musashi-2 and Decreased NUMB Protein Levels Observed in Human Colorectal Cancer are reverted to Normal Levels by ATRA-Induced Cell Differentiation

por Opdenaker, Lynn M, Kowash, Ryan, Masters, Gabriel, Boman, Bruce M, Zhang, Tao, Modarai, Shirin R
Publicado en Int J Cancer Res Ther (2018)

Identification of a Developmental Gene Expression Signature, Including HOX Genes, for the Normal Human Colonic Crypt Stem Cell Niche: Overexpression of the Signature Parallels Stem...

por Bhatlekar, Seema, Addya, Sankar, Salunek, Moreh, Orr, Christopher R., Surrey, Saul, McKenzie, Steven, Fields, Jeremy Z., Boman, Bruce M.
Publicado 2014

Colonic Crypt Changes during Adenoma Development in Familial Adenomatous Polyposis : Immunohistochemical Evidence for Expansion of the Crypt Base Cell Population

por Boman, Bruce M., Walters, Rhonda, Fields, Jeremy Z., Kovatich, Albert J., Zhang, Tao, Isenberg, Gerald A., Goldstein, Scott D., Palazzo, Juan P.
Publicado 2004

Aldehyde Dehydrogenase 1 Is a Marker for Normal and Malignant Human Colonic Stem Cells (SC) and Tracks SC Overpopulation during Colon Tumorigenesis

por Huang, Emina H., Hynes, Mark J., Zhang, Tao, Ginestier, Christophe, Dontu, Gabriela, Appelman, Henry, Fields, Jeremy Z., Wicha, Max S., Boman, Bruce M.
Publicado 2009

Detection of DNA mismatch repair proteins in fresh human blood lymphocytes - towards a novel method for hereditary non-polyposis colorectal cancer (Lynch syndrome) screening

por Hassen, Samar, Boman, Bruce M, Ali, Nawab, Parker, Marcie, Somerman, Chandra, Ali-Khan Catts, Zohra J, Ali, Akhtar A, Fields, Jeremy Z
Publicado 2011

The anti-cancer effect of retinoic acid signaling in CRC occurs via decreased growth of ALDH+ colon cancer stem cells and increased differentiation of stem cells

por Modarai, Shirin R., Gupta, Anindita, Opdenaker, Lynn M., Kowash, Ryan, Masters, Gabriel, Viswanathan, Vignesh, Zhang, Tao, Fields, Jeremy Z., Boman, Bruce M.
Publicado en Oncotarget (2018)

APC mutations in human colon lead to decreased neuroendocrine maturation of ALDH+ stem cells that alters GLP-2 and SST feedback signaling: Clue to a link between WNT and retinoic a...

por Zhang, Tao, Ahn, Koree, Emerick, Brooks, Modarai, Shirin R., Opdenaker, Lynn M., Palazzo, Juan, Schleiniger, Gilberto, Fields, Jeremy Z., Boman, Bruce M.
Publicado en PLoS One (2020)

Survivin-Induced Aurora-B Kinase Activation : A Mechanism by Which APC Mutations Contribute to Increased Mitoses during Colon Cancer Development

por Zhang, Tao, Fields, Jeremy Z., Opdenaker, Lynn, Otevrel, Tomas, Masuda, Emi, Palazzo, Juan P., Isenberg, Gerald A., Goldstein, Scott D., Brand, Marc, Boman, Bruce M.
Publicado 2010

Discovery of Power-Law Growth in the Self-Renewal of Heterogeneous Glioma Stem Cell Populations

por Sugimori, Michiya, Hayakawa, Yumiko, Boman, Bruce M., Fields, Jeremy Z., Awaji, Miharu, Kozano, Hiroko, Tamura, Ryoi, Yamamoto, Seiji, Ogata, Toru, Yamada, Mitsuhiko, Endo, Shunro, Kurimoto, Masanori, Kuroda, Satoshi
Publicado en PLoS One (2015)

One-hit effects in cancer: Altered proteome of morphologically normal colon crypts in Familial Adenomatous Polyposis

por Yeung, Anthony T., Patel, Bhavinkumar B., Li, Xin-Ming, Seeholzer, Steven H., Coudry, Renata A., Cooper, Harry S., Bellacosa, Alfonso, Boman, Bruce M., Zhang, Tao, Litwin, Samuel, Ross, Eric A., Conrad, Peggy, Crowell, James A., Kopelovich, Levy, Knudson, Alfred
Publicado 2008

APC(+/−) alters colonic fibroblast proteome in FAP

por Patel, Bhavinkumar B., Li, Xin-Ming, Dixon, Maketa P., Blagoi, Elena L., Nicolas, Emmanuelle, Seeholzer, Steven H., Cheng, David, He, Yin A., Coudry, Renata A., Howard, Sharon D., Riddle, Dawn M., Cooper, Harry S., Boman, Bruce M., Conrad, Peggy, Crowell, James A., Bellacosa, Alfonso, Knudson, Alfred, Yeung, Anthony T., Kopelovich, Levy
Publicado 2011