Aldehyde Dehydrogenase 1 Is a Marker for Normal and Malignant Human Colonic Stem Cells (SC) and Tracks SC Overpopulation during Colon Tumorigenesis

Although the concept that cancers originate from stem cells (SC) is becoming scientifically accepted, mechanisms by which SC contribute to tumor initiation and progression are largely unknown. For colorectal cancer (CRC), investigation of this problem has been hindered by a paucity of specific marke...

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Main Authors: Huang, Emina H., Hynes, Mark J., Zhang, Tao, Ginestier, Christophe, Dontu, Gabriela, Appelman, Henry, Fields, Jeremy Z., Wicha, Max S., Boman, Bruce M.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789401/
https://ncbi.nlm.nih.gov/pubmed/19336570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4418
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