A decisive function of transforming growth factor-β/Smad signaling in tissue morphogenesis and differentiation of human HaCaT keratinocytes

Por Buschke, Susanne, Stark, Hans-Jürgen, Cerezo, Ana, Prätzel-Wunder, Silke, Boehnke, Karsten, Kollar, Jasmin, Langbein, Lutz, Heldin, Carl-Henrik, Boukamp, Petra
Publicado em 2011

Assay Establishment and Validation of a High-Throughput Screening Platform for Three-Dimensional Patient-Derived Colon Cancer Organoid Cultures

Por Boehnke, Karsten, Iversen, Philip W., Schumacher, Dirk, Lallena, María José, Haro, Rubén, Amat, Joaquín, Haybaeck, Johannes, Liebs, Sandra, Lange, Martin, Schäfer, Reinhold, Regenbrecht, Christian R. A., Reinhard, Christoph, Velasco, Juan A.
Publicado no SLAS Discov (2016)

Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures

Por Schumacher, Dirk, Andrieux, Geoffroy, Boehnke, Karsten, Keil, Marlen, Silvestri, Alessandra, Silvestrov, Maxine, Keilholz, Ulrich, Haybaeck, Johannes, Erdmann, Gerrit, Sachse, Christoph, Templin, Markus, Hoffmann, Jens, Boerries, Melanie, Schäfer, Reinhold, Regenbrecht, Christian R. A.
Publicado no PLoS Genet (2019)

Preclinical characterization of abemaciclib in hormone receptor positive breast cancer

Por Torres-Guzmán, Raquel, Calsina, Bruna, Hermoso, Ana, Baquero, Carmen, Alvarez, Beatriz, Amat, Joaquín, McNulty, Ann M., Gong, Xueqian, Boehnke, Karsten, Du, Jian, de Dios, Alfonso, Beckmann, Richard P., Buchanan, Sean, Lallena, María José
Publicado no Oncotarget (2017)

Combined inhibition of PIM and CDK4/6 suppresses both mTOR signaling and Rb phosphorylation and potentiates PI3K inhibition in cancer cells

Por Litchfield, Lacey M., Boehnke, Karsten, Brahmachary, Manisha, Mur, Cecilia, Bi, Chen, Stephens, Jennifer R., Sauder, J. Michael, Gutiérrez, Sonia M., McNulty, Ann M., Ye, Xiang S., Wu, Wenjuan, Lallena, María José, Gong, Xueqian, Merzoug, Farhana F., Jansen, Valerie M., Buchanan, Sean G.
Publicado no Oncotarget (2020)

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib

Por Blosser, Wayne D., Dempsey, Jack A., McNulty, Ann M., Rao, Xi, Ebert, Philip J., Lowery, Caitlin D., Iversen, Philip W., Webster, Yue Wang, Donoho, Gregory P., Gong, Xueqian, Merzoug, Farhana F., Buchanan, Sean, Boehnke, Karsten, Yu, Chunping, You, Xin Tian, Beckmann, Richard P., Wu, Wenjuan, McNeely, Samuel C., Lin, Aimee Bence, Martinez, Ricardo
Publicado no Oncotarget (2020)

Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors

Por Schütte, Moritz, Risch, Thomas, Abdavi-Azar, Nilofar, Boehnke, Karsten, Schumacher, Dirk, Keil, Marlen, Yildiriman, Reha, Jandrasits, Christine, Borodina, Tatiana, Amstislavskiy, Vyacheslav, Worth, Catherine L., Schweiger, Caroline, Liebs, Sandra, Lange, Martin, Warnatz, Hans- Jörg, Butcher, Lee M., Barrett, James E., Sultan, Marc, Wierling, Christoph, Golob-Schwarzl, Nicole, Lax, Sigurd, Uranitsch, Stefan, Becker, Michael, Welte, Yvonne, Regan, Joseph Lewis, Silvestrov, Maxine, Kehler, Inge, Fusi, Alberto, Kessler, Thomas, Herwig, Ralf, Landegren, Ulf, Wienke, Dirk, Nilsson, Mats, Velasco, Juan A., Garin-Chesa, Pilar, Reinhard, Christoph, Beck, Stephan, Schäfer, Reinhold, Regenbrecht, Christian R. A., Henderson, David, Lange, Bodo, Haybaeck, Johannes, Keilholz, Ulrich, Hoffmann, Jens, Lehrach, Hans, Yaspo, Marie-Laure
Publicado no Nat Commun (2017)