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A decisive function of transforming growth factor-β/Smad signaling in tissue morphogenesis and differentiation of human HaCaT keratinocytes

 The mechanism by which transforming growth factor-β (TGFβ) regulates differentiation in human epidermal keratinocytes is still poorly understood. To assess the role of Smad signaling, we engineered human HaCaT keratinocytes either expressing small interfering RNA against Smads2, 3, and 4 or overexp...

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Detalhes bibliográficos
Main Authors: Buschke, Susanne, Stark, Hans-Jürgen, Cerezo, Ana, Prätzel-Wunder, Silke, Boehnke, Karsten, Kollar, Jasmin, Langbein, Lutz, Heldin, Carl-Henrik, Boukamp, Petra
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057703/
https://ncbi.nlm.nih.gov/pubmed/21289094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-11-0879
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