Heterogeneous pathway activation and drug response modelled in colorectal-tumor-derived 3D cultures

Organoid cultures derived from colorectal cancer (CRC) samples are increasingly used as preclinical models for studying tumor biology and the effects of targeted therapies under conditions capturing in vitro the genetic make-up of heterogeneous and even individual neoplasms. While 3D cultures are in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Schumacher, Dirk, Andrieux, Geoffroy, Boehnke, Karsten, Keil, Marlen, Silvestri, Alessandra, Silvestrov, Maxine, Keilholz, Ulrich, Haybaeck, Johannes, Erdmann, Gerrit, Sachse, Christoph, Templin, Markus, Hoffmann, Jens, Boerries, Melanie, Schäfer, Reinhold, Regenbrecht, Christian R. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457557/
https://ncbi.nlm.nih.gov/pubmed/30925167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008076
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados