Genetics Of Human Origin and Evolution: High-Altitude Adaptations

Por Bigham, Abigail W.
Publicado no Curr Opin Genet Dev (2016)

Human high-altitude adaptation: forward genetics meets the HIF pathway

Por Bigham, Abigail W., Lee, Frank S.
Publicado em 2014

Estimates of Continental Ancestry Vary Widely among Individuals with the Same mtDNA Haplogroup

Por Emery, Leslie S., Magnaye, Kevin M., Bigham, Abigail W., Akey, Joshua M., Bamshad, Michael J.
Publicado no Am J Hum Genet (2015)

Association of the OCA2 Polymorphism His615Arg with Melanin Content in East Asian Populations: Further Evidence of Convergent Evolution of Skin Pigmentation

Por Edwards, Melissa, Bigham, Abigail, Tan, Jinze, Li, Shilin, Gozdzik, Agnes, Ross, Kendra, Jin, Li, Parra, Esteban J.
Publicado em 2010

Heterogeneous patterns of variation among multiple human x-linked Loci: the possible role of diversity-reducing selection in non-africans.

Por Hammer, Michael F, Garrigan, Daniel, Wood, Elizabeth, Wilder, Jason A, Mobasher, Zahra, Bigham, Abigail, Krenz, James G, Nachman, Michael W
Publicado em 2004

Uncoupling Protein 2 Ala55Val polymorphism is associated with a higher acute insulin response to glucose

Por Willig, Amanda L., Casazza, Krista R., Divers, Jasmin, Bigham, Abigail W., Gower, Barbara A., Hunter, Gary R., Fernandez, Jose R
Publicado em 2009

Angiotensin-Converting Enzyme Genotype and Arterial Oxygen Saturation at High Altitude in Peruvian Quechua

Por Bigham, Abigail W., Kiyamu, Melisa, León-Velarde, Fabiola, Parra, Esteban J., Rivera-Ch, Maria, Shriver, Mark D., Brutsaert, Tom D.
Publicado em 2008

Maternal PRKAA1 and EDNRA genotypes are associated with birth weight, and PRKAA1 with uterine artery diameter and metabolic homeostasis at high altitude

Por Bigham, Abigail W., Julian, Colleen G., Wilson, Megan J., Vargas, Enrique, Browne, Vaughn A., Shriver, Mark D., Moore, Lorna G.
Publicado em 2014

Defective Tibetan PHD2 Binding to p23 Links High Altitude Adaption to Altered Oxygen Sensing

Por Song, Daisheng, Li, Lin-sheng, Arsenault, Patrick R., Tan, Qiulin, Bigham, Abigail W., Heaton-Johnson, Katherine J., Master, Stephen R., Lee, Frank S.
Publicado em 2014

Identity-by-descent filtering of exome sequence data for disease–gene identification in autosomal recessive disorders

Por Rödelsperger, Christian, Krawitz, Peter, Bauer, Sebastian, Hecht, Jochen, Bigham, Abigail W., Bamshad, Michael, de Condor, Birgit Jonske, Schweiger, Michal R., Robinson, Peter N.
Publicado em 2011

Do Anti-angiogenic or Angiogenic Factors Contribute to the Protection of Birth Weight at High Altitude Afforded by Andean Ancestry?

Por Dávila, R. Daniela, Julian, Colleen G., Wilson, Megan J., Browne, Vaughn A., Rodriguez, Carmelo, Bigham, Abigail W., Shriver, Mark D., Vargas, Enrique, Moore, Lorna G.
Publicado em 2010

Do Cytokines Contribute to the Andean-Associated Protection From Reduced Fetal Growth at High Altitude?

Por Daniela Dávila, R., Julian, Colleen G., Wilson, Megan J., Browne, Vaughn A., Rodriguez, Carmelo, Bigham, Abigail W., Shriver, Mark D., Vargas, Enrique, Moore, Lorna G.
Publicado em 2011

Augmented uterine artery blood flow and oxygen delivery protect Andeans from altitude-associated reductions in fetal growth

Por Julian, Colleen Glyde, Wilson, Megan J., Lopez, Miriam, Yamashiro, Henry, Tellez, Wilma, Rodriguez, Armando, Bigham, Abigail W., Shriver, Mark D., Rodriguez, Carmelo, Vargas, Enrique, Moore, Lorna G.
Publicado em 2009

Identifying positive selection candidate loci for high-altitude adaptation in Andean populations

Por Bigham, Abigail W, Mao, Xianyun, Mei, Rui, Brutsaert, Tom, Wilson, Megan J, Julian, Colleen Glyde, Parra, Esteban J, Akey, Joshua M, Moore, Lorna G, Shriver, Mark D
Publicado em 2009

Toll-like Receptor (TLR) variants are associated with infant HIV-1 acquisition and peak plasma HIV-1 RNA level

Por BEIMA-SOFIE, Kristin M., BIGHAM, Abigail W., LINGAPPA, Jairam R., WAMALWA, Dalton, MACKELPRANG, Romel D., Bamshad, Michael J., MALECHE-OBIMBO, Elizabeth, RICHARDSON, Barbra A., JOHN-STEWART, Grace C.
Publicado em 2013

Toll-like receptor gene variants and bacterial vaginosis among HIV-1 infected and uninfected African women

Por Mackelprang, Romel D., Scoville, Caitlin Wright, Cohen, Craig R., Ondondo, Raphael Omusebe, Bigham, Abigail W., Celum, Connie, Campbell, Mary S., Essex, Max, Wald, Anna, Kiarie, James, Ronald, Allan, Gray, Glenda, Lingappa, Jairam R.
Publicado no Genes Immun (2015)

A Genomewide Admixture Mapping Panel for Hispanic/Latino Populations

Por Mao, Xianyun , Bigham, Abigail W. , Mei, Rui , Gutierrez, Gerardo , Weiss, Ken M. , Brutsaert, Tom D. , Leon-Velarde, Fabiola , Moore, Lorna G. , Vargas, Enrique , McKeigue, Paul M. , Shriver, Mark D. , Parra, Esteban J. 
Publicado em 2007

Targeted Capture and Massively Parallel Sequencing of Twelve Human Exomes

Por Ng, Sarah B., Turner, Emily H., Robertson, Peggy D., Flygare, Steven D., Bigham, Abigail W., Lee, Choli, Shaffer, Tristan, Wong, Michelle, Bhattacharjee, Arindam, Eichler, Evan E., Bamshad, Michael, Nickerson, Deborah A., Shendure, Jay
Publicado em 2009

Exome sequencing identifies the cause of a Mendelian disorder

Por Ng, Sarah B., Buckingham, Kati J., Lee, Choli, Bigham, Abigail W., Tabor, Holly K., Dent, Karin M., Huff, Chad D., Shannon, Paul T., Jabs, Ethylin Wang, Nickerson, Deborah A., Shendure, Jay, Bamshad, Michael J.
Publicado em 2009

Identifying Signatures of Natural Selection in Tibetan and Andean Populations Using Dense Genome Scan Data

Por Bigham, Abigail, Bauchet, Marc, Pinto, Dalila, Mao, Xianyun, Akey, Joshua M., Mei, Rui, Scherer, Stephen W., Julian, Colleen G., Wilson, Megan J., López Herráez, David, Brutsaert, Tom, Parra, Esteban J., Moore, Lorna G., Shriver, Mark D.
Publicado em 2010