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Human high-altitude adaptation: forward genetics meets the HIF pathway
Humans have adapted to the chronic hypoxia of high altitude in several locations, and recent genome-wide studies have indicated a genetic basis. In some populations, genetic signatures have been identified in the hypoxia-inducible factor (HIF) pathway, which orchestrates the transcriptional response...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4201282/ https://ncbi.nlm.nih.gov/pubmed/25319824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.250167.114 |
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