Disease Progression Modeling: Key Concepts and Recent Developments

Por Cook, Sarah F., Bies, Robert R.
Publicado no Curr Pharmacol Rep (2016)

Bayesian model of Hamilton Depression Rating Score (HDRS) with memantine augmentation in bipolar depression

Por Stevens, Jasper, Bies, Robert R., Shekhar, Anantha, Anand, Amit
Publicado em 2013

Big Data: Challenges and opportunities for clinical pharmacology

Por Flockhart, David, Bies, Robert R., Gastonguay, Marc R., Schwartz, Sorell L.
Publicado no Br J Clin Pharmacol (2016)

Clinical Trial Simulation to Evaluate Population Pharmacokinetics and Food Effect: Capturing Abiraterone and Nilotinib Exposures

Por Li, Claire H., Sherer, Eric A., Lewis, Lionel D., Bies, Robert R.
Publicado no J Clin Pharmacol (2015)

Cardiac Arrest and Therapeutic Hypothermia Decrease Isoform-Specific Cytochrome P450 Drug Metabolism

Por Zhou, Jiangquan, Empey, Philip E., Bies, Robert R., Kochanek, Patrick M., Poloyac, Samuel M.
Publicado em 2011

Population pharmacokinetic modeling of risperidone and 9-hydroxyrisperidone to estimate CYP2D6 subpopulations in children and adolescents

Por Sherwin, Catherine M. T., Saldaña, Shannon N., Bies, Robert R., Aman, Michael G., Vinks, Alexander A.
Publicado em 2012

Nicotine and Cotinine Exposure from Electronic Cigarettes: A Population Approach

Por de Mendizábal, Nieves Vélez, Jones, David R., Jahn, Andy, Bies, Robert R., Brown, Joshua W.
Publicado no Clin Pharmacokinet (2015)

Performance of Cpred/Cobs concentration ratios as a metric reflecting adherence to antidepressant drug therapy

Por Feng, Yan, Gastonguay, Marc R, Pollock, Bruce G, Frank, Ellen, Kepple, Gail H, Bies, Robert R
Publicado em 2011

Development of a dosage strategy in patients receiving enoxaparin by continuous intravenous infusion using modelling and simulation

Por Feng, Yan, Green, Bruce, Duffull, Stephen B, Kane-Gill, Sandra L, Bobek, Mary B, Bies, Robert R
Publicado em 2006

Paroxetine: population pharmacokinetic analysis in late-life depression using sparse concentration sampling

Por Feng, Yan, Pollock, Bruce G, Ferrell, Robert E, Kimak, Mark A, Reynolds, Charles F, Bies, Robert R
Publicado em 2006

Translocator Receptor Blockade Reduces Prostate Tumor Growth

Por Fafalios, Arlee, Akhavan, Ardavan, Parwani, Anil V., Bies, Robert R., McHugh, Kevin J., Pflug, Beth R.
Publicado em 2009

Genetic Variation in CYP3A43 Explains Racial Difference in Olanzapine Clearance

Por Bigos, Kristin L., Bies, Robert R., Pollock, Bruce G., Lowy, Joshua J., Zhang, Fengyu, Weinberger, Daniel R.
Publicado em 2011

Acute 5-HT Reuptake Blockade Potentiates Human Amygdala Reactivity

Por Bigos, Kristin L, Pollock, Bruce G, Aizenstein, Howard J, Fisher, Patrick M, Bies, Robert R, Hariri, Ahmad R
Publicado em 2008

Tardive Dyskinesia in Relation to Estimated Dopamine D2 Receptor Occupancy in Patients with Schizophrenia: Analysis of the CATIE data

Por Yoshida, Kazunari, Bies, Robert R., Suzuki, Takefumi, Remington, Gary, Pollock, Bruce G., Mizuno, Yuya, Mimura, Masaru, Uchida, Hiroyuki
Publicado em 2014

Population Pharmacokinetic Modeling To Estimate the Contributions of Genetic and Nongenetic Factors to Efavirenz Disposition

Por Robarge, Jason D., Metzger, Ingrid F., Lu, Jessica, Thong, Nancy, Skaar, Todd C., Desta, Zeruesenay, Bies, Robert R.
Publicado no Antimicrob Agents Chemother (2016)

PM398. Fluctuations in hallucinatory experiences within a day in relation to dopamine D2 receptor blockade with antipsychotics in patients with schizophrenia

Por Koizumi, Teruki, Suzuki, Takefumi, Bies, Robert R., Pollock, Bruce G., Endo, Aki, Ohtani, Ai, Mimura, Masaru, Uchida, Hiroyuki
Publicado no Int J Neuropsychopharmacol (2016)

Predicting Relapsing-Remitting Dynamics in Multiple Sclerosis Using Discrete Distribution Models: A Population Approach

Por Velez de Mendizabal, Nieves, Hutmacher, Matthew M., Troconiz, Iñaki F., Goñi, Joaquín, Villoslada, Pablo, Bagnato, Francesca, Bies, Robert R.
Publicado em 2013

Correction: Predicting Relapsing-Remitting Dynamics in Multiple Sclerosis Using Discrete Distribution Models: A Population Approach

Por Velez de Mendizabal, Nieves, Hutmacher, Matthew M., Troconiz, Iñaki F., Goñi, Joaquín, Villoslada, Pablo, Bagnato, Francesca, Bies, Robert R.
Publicado em 2014

Population pharmacokinetic analysis for risperidone using highly sparse sampling measurements from the CATIE study

Por Feng, Yan, Pollock, Bruce G, Coley, Kim, Marder, Stephen, Miller, Del, Kirshner, Margaret, Aravagiri, Manickam, Schneider, Lon, Bies, Robert R
Publicado em 2008

Resampling phase III data to assess phase II trial designs and endpoints

Por Sharma, Manish R., Karrison, Theodore G., Jin, Yuyan, Bies, Robert R., Maitland, Michael L., Stadler, Walter M., Ratain, Mark J.
Publicado em 2012